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Home 〉 LSI Community 〉 Dr Akshay Bhinge

Dr Akshay Bhinge

Lecturer


A.Bhinge@exeter.ac.uk
CMH
Groups: Bhinge Group
University profile
0000-0003-2939-099X

Publications

2022

Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis

Journal: Stem Cell Reports
Published: 31/05/2022
DOI: 10.1016/j.stemcr.2022.05.019
ISSN: 2213-6711
URL: http://dx.doi.org/10.1016/j.stemcr.2022.05.019


2021

Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Journal: Molecular Brain
Published: 30/11/2021
DOI: 10.1186/s13041-021-00810-w
ISSN: 1756-6606
URL: http://dx.doi.org/10.1186/s13041-021-00810-w

Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons.

Journal: Stem cell reports
Published: 31/10/2021
PMID: 34767750
PMC: PMC8693652
DOI: 10.1016/j.stemcr.2021.10.010
URL: http://europepmc.org/abstract/med/34767750


2017

Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis.

Journal: Stem cell reports
Published: 30/03/2017
PMID: 28366453
PMC: PMC5390134
DOI: 10.1016/j.stemcr.2017.02.019
URL: http://europepmc.org/articles/PMC5390134


2016

Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis

Journal: Molecular and cellular biology
Published: 30/11/2016
DOI: 10.1128/MCB.00201-17
URL: http://europepmc.org/articles/PMC5533875

Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis

Journal: Stem cell reports
Published: 30/11/2016
DOI: 10.1016/j.stemcr.2017.02.019
URL: http://europepmc.org/articles/PMC5390134

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

Journal: Genome research
Published: 30/11/2016
DOI: 10.1101/gr.223313.117
URL: http://europepmc.org/articles/PMC5668937


2015

MiR-375 is Essential for Human Spinal Motor Neuron Development and May Be Involved in Motor Neuron Degeneration

Journal: STEM CELLS
Published: 31/12/2015
DOI: 10.1002/stem.2233
ISSN: 1066-5099
URL: http://dx.doi.org/10.1002/stem.2233


2014

NeuO: a fluorescent chemical probe for live neuron labeling

Journal: Angewandte Chemie (International ed. in English)
Published: 30/11/2014
DOI: 10.1002/anie.201408614
URL: https://doi.org/10.1002/anie.201408614

MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling.

Journal: The EMBO journal
Published: 06/05/2014
PMID: 24802670
PMC: PMC4198029
DOI: 10.1002/embj.201387215
URL: http://europepmc.org/articles/PMC4198029


2013

MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling

Journal: The EMBO journal
Published: 30/11/2013
DOI: 10.1002/embj.201387215
URL: http://europepmc.org/articles/PMC4198029


2012

A Myc-microRNA network promotes exit from quiescence by suppressing the interferon response and cell-cycle arrest genes

Journal: Nucleic acids research
Published: 30/11/2012
DOI: 10.1093/nar/gks1452
URL: http://europepmc.org/articles/PMC3575845


2011

A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes

Journal: PLoS genetics
Published: 30/11/2011
DOI: 10.1371/journal.pgen.1002624
URL: http://europepmc.org/articles/PMC3320604

An integrated encyclopedia of DNA elements in the human genome

Journal: Nature
Published: 30/11/2011
DOI: 10.1038/nature11247
URL: http://europepmc.org/articles/PMC3439153

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

Journal: Genome research
Published: 30/11/2011
DOI: 10.1101/gr.127597.111
URL: http://europepmc.org/articles/PMC3246210


2010

A user’s guide to the encyclopedia of DNA elements (ENCODE)

Journal: PLoS biology
Published: 30/11/2010
DOI: 10.1371/journal.pbio.1001046
URL: http://europepmc.org/articles/PMC3079585

Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis

Journal: Nucleic acids research
Published: 30/11/2010
DOI: 10.1093/nar/gkq1313
URL: http://europepmc.org/articles/PMC3089461


2008

Epigenetics of human T cells during the G0–>G1 transition

Journal: Genome research
Published: 30/11/2008
DOI: 10.1101/gr.085530.108
URL: http://europepmc.org/articles/PMC2720178


2007

Dynamic remodeling of individual nucleosomes across a eukaryotic genome in response to transcriptional perturbation

Journal: PLoS biology
Published: 30/11/2007
DOI: 10.1371/journal.pbio.0060065
URL: http://europepmc.org/articles/PMC2267817


2006

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Journal: Nature
Published: 30/11/2006
DOI: 10.1038/nature05874
URL: http://europepmc.org/articles/PMC2212820

Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic Enrichment (STAGE)

Journal: Genome research
Published: 30/11/2006
DOI: 10.1101/gr.5574907
URL: http://europepmc.org/articles/PMC1891349


2004

Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment

Journal: Nature methods
Published: 30/11/2004
DOI: 10.1038/nmeth726
URL: https://doi.org/10.1038/nmeth726


2003

Accurate detection of protein:ligand binding sites using molecular dynamics simulations

Journal: Structure (London, England : 1993)
Published: 30/11/2003
DOI: 10.1016/j.str.2004.09.005
URL: https://doi.org/10.1016/j.str.2004.09.005

Role of L-lysine HCl in adoptive immune therapy towards development of suitable tuberculosis vaccination

Journal: Indian journal of experimental biology
Published: 30/11/2003
URL: http://europepmc.org/abstract/MED/15573523


2002

Role of L-lysine HCl in immunopotentiation towards development of suitable tuberculosis vaccination

Journal: Vaccine
Published: 30/11/2002
DOI: 10.1016/s0264-410x(03)00513-9
URL: https://doi.org/10.1016/S0264-410X(03)00513-9


2001

A procedure for detection and quantitation of cavity volumes proteins. Application to measure the strength of the hydrophobic driving force in protein folding

Journal: The Journal of biological chemistry
Published: 30/11/2001
DOI: 10.1074/jbc.m201373200
URL: https://doi.org/10.1074/jbc.M201373200


2000

Lysine: Is it worth more?

Journal: Cytotechnology
Published: 30/11/2000
DOI: 10.1023/A:1014097121364
URL: http://europepmc.org/articles/PMC3449675


1999

Effect of cationic amino acid, L-lysine and its polymers on the growth and secretion of hybridoma cell line OKT-3

Journal: Hybridoma
Published: 30/11/1999
DOI: 10.1089/027245700429909
URL: https://doi.org/10.1089/027245700429909

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