Dr Akshay Bhinge Senior Lecturer A.Bhinge@exeter.ac.uk CMH Groups: Bhinge Group University profile 0000-0003-2939-099X Publications Publications 2022 Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis. Journal: Stem cell reports Published: 23/06/2022 PMID: 35750046 PMC: PMC9287677 DOI: 10.1016/j.stemcr.2022.05.019 URL: https://europepmc.org/articles/PMC9287677 Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis Journal: Stem Cell Reports Published: 31/05/2022 DOI: 10.1016/j.stemcr.2022.05.019 ISSN: 2213-6711 URL: http://dx.doi.org/10.1016/j.stemcr.2022.05.019 2021 Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons Journal: Molecular Brain Published: 30/11/2021 DOI: 10.1186/s13041-021-00810-w ISSN: 1756-6606 URL: http://dx.doi.org/10.1186/s13041-021-00810-w Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons. Journal: Stem cell reports Published: 31/10/2021 PMID: 34767750 PMC: PMC8693652 DOI: 10.1016/j.stemcr.2021.10.010 URL: http://europepmc.org/abstract/med/34767750 2017 Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis. Journal: Stem cell reports Published: 30/03/2017 PMID: 28366453 PMC: PMC5390134 DOI: 10.1016/j.stemcr.2017.02.019 URL: http://europepmc.org/articles/PMC5390134 2016 Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis Journal: Molecular and cellular biology Published: 30/11/2016 DOI: 10.1128/MCB.00201-17 URL: http://europepmc.org/articles/PMC5533875 Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis Journal: Stem cell reports Published: 30/11/2016 DOI: 10.1016/j.stemcr.2017.02.019 URL: http://europepmc.org/articles/PMC5390134 Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons Journal: Genome research Published: 30/11/2016 DOI: 10.1101/gr.223313.117 URL: http://europepmc.org/articles/PMC5668937 2015 MiR-375 is Essential for Human Spinal Motor Neuron Development and May Be Involved in Motor Neuron Degeneration Journal: STEM CELLS Published: 31/12/2015 DOI: 10.1002/stem.2233 ISSN: 1066-5099 URL: http://dx.doi.org/10.1002/stem.2233 2014 NeuO: a fluorescent chemical probe for live neuron labeling Journal: Angewandte Chemie (International ed. in English) Published: 30/11/2014 DOI: 10.1002/anie.201408614 URL: https://doi.org/10.1002/anie.201408614 MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling. Journal: The EMBO journal Published: 06/05/2014 PMID: 24802670 PMC: PMC4198029 DOI: 10.1002/embj.201387215 URL: http://europepmc.org/articles/PMC4198029 2013 MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling Journal: The EMBO journal Published: 30/11/2013 DOI: 10.1002/embj.201387215 URL: http://europepmc.org/articles/PMC4198029 2012 A Myc-microRNA network promotes exit from quiescence by suppressing the interferon response and cell-cycle arrest genes Journal: Nucleic acids research Published: 30/11/2012 DOI: 10.1093/nar/gks1452 URL: http://europepmc.org/articles/PMC3575845 2011 A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes Journal: PLoS genetics Published: 30/11/2011 DOI: 10.1371/journal.pgen.1002624 URL: http://europepmc.org/articles/PMC3320604 An integrated encyclopedia of DNA elements in the human genome Journal: Nature Published: 30/11/2011 DOI: 10.1038/nature11247 URL: http://europepmc.org/articles/PMC3439153 Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells Journal: Genome research Published: 30/11/2011 DOI: 10.1101/gr.127597.111 URL: http://europepmc.org/articles/PMC3246210 2010 A user’s guide to the encyclopedia of DNA elements (ENCODE) Journal: PLoS biology Published: 30/11/2010 DOI: 10.1371/journal.pbio.1001046 URL: http://europepmc.org/articles/PMC3079585 Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis Journal: Nucleic acids research Published: 30/11/2010 DOI: 10.1093/nar/gkq1313 URL: http://europepmc.org/articles/PMC3089461 2008 Epigenetics of human T cells during the G0–>G1 transition Journal: Genome research Published: 30/11/2008 DOI: 10.1101/gr.085530.108 URL: http://europepmc.org/articles/PMC2720178 2007 Dynamic remodeling of individual nucleosomes across a eukaryotic genome in response to transcriptional perturbation Journal: PLoS biology Published: 30/11/2007 DOI: 10.1371/journal.pbio.0060065 URL: http://europepmc.org/articles/PMC2267817 2006 Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Journal: Nature Published: 30/11/2006 DOI: 10.1038/nature05874 URL: http://europepmc.org/articles/PMC2212820 Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic Enrichment (STAGE) Journal: Genome research Published: 30/11/2006 DOI: 10.1101/gr.5574907 URL: http://europepmc.org/articles/PMC1891349 2004 Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment Journal: Nature methods Published: 30/11/2004 DOI: 10.1038/nmeth726 URL: https://doi.org/10.1038/nmeth726 2003 Accurate detection of protein:ligand binding sites using molecular dynamics simulations Journal: Structure (London, England : 1993) Published: 30/11/2003 DOI: 10.1016/j.str.2004.09.005 URL: https://doi.org/10.1016/j.str.2004.09.005 Role of L-lysine HCl in adoptive immune therapy towards development of suitable tuberculosis vaccination Journal: Indian journal of experimental biology Published: 30/11/2003 URL: http://europepmc.org/abstract/MED/15573523 2002 Role of L-lysine HCl in immunopotentiation towards development of suitable tuberculosis vaccination Journal: Vaccine Published: 30/11/2002 DOI: 10.1016/s0264-410x(03)00513-9 URL: https://doi.org/10.1016/S0264-410X(03)00513-9 2001 A procedure for detection and quantitation of cavity volumes proteins. Application to measure the strength of the hydrophobic driving force in protein folding Journal: The Journal of biological chemistry Published: 30/11/2001 DOI: 10.1074/jbc.m201373200 URL: https://doi.org/10.1074/jbc.M201373200 2000 Lysine: Is it worth more? Journal: Cytotechnology Published: 30/11/2000 DOI: 10.1023/A:1014097121364 URL: http://europepmc.org/articles/PMC3449675 1999 Effect of cationic amino acid, L-lysine and its polymers on the growth and secretion of hybridoma cell line OKT-3 Journal: Hybridoma Published: 30/11/1999 DOI: 10.1089/027245700429909 URL: https://doi.org/10.1089/027245700429909