Dr Ge Guo Senior Research Fellow G.Guo@exeter.ac.uk CLES Groups: Guo Group University profile 0000-0002-3273-9147 Publications Publications 2024 A new resource of clonal pluripotent human stem cell lines exhibiting inter- and intra-embryo consistency and variability Journal: Biorxiv Published: 30/11/2024 DOI: 10.1101/2025.06.02.657331 EID: 2-s2.0-105012646717 ISSN: 26928205 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-105012646717&partnerID=MN8TOARS Inhibition of PRC2 enables self-renewal of blastoid-competent naive pluripotent stem cells from chimpanzee Journal: Cell Stem Cell Published: 30/11/2024 DOI: 10.1016/j.stem.2025.02.002 EID: 2-s2.0-105000753728 ISSN: 19345909 18759777 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-105000753728&partnerID=MN8TOARS Naive pluripotent stem cell-based models capture FGF-dependent human hypoblast lineage specification. Journal: Cell Stem Cell Published: 30/06/2024 DOI: 10.1016/j.stem.2024.05.003 ISSN: 1934-5909 URL: http://dx.doi.org/10.1016/j.stem.2024.05.003 2023 Human naïve stem cell models reveal the role of FGF in hypoblast specification in the human embryo Published: 30/11/2023 PPR: PPR767982 DOI: 10.1101/2023.11.30.569161 URL: http://europepmc.org/abstract/PPR/PPR767982 Monochorionic Twinning in Bioengineered Human Embryo Models Journal: Advanced Materials Published: 30/11/2023 DOI: 10.1002/adma.202313306 EID: 2-s2.0-85190502680 ISSN: 09359648 15214095 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-85190502680&partnerID=MN8TOARS 2022 Biophysical models of early mammalian embryogenesis. Journal: Stem cell reports Published: 31/12/2022 PMID: 36630902 PMC: PMC9860129 DOI: 10.1016/j.stemcr.2022.11.021 URL: http://europepmc.org/abstract/med/36630902 Suppression of YAP Safeguards Human Naïve Pluripotency Journal: Development Published: 15/12/2022 DOI: 10.1242/dev.200988 URL: https://doi.org/10.1242/dev.200988 2021 Deriving Human Naïve Embryonic Stem Cell Lines from Donated Supernumerary Embryos Using Physical Distancing and Signal Inhibition Journal: Methods in Molecular Biology Published: 30/11/2021 DOI: 10.1007/978-1-0716-1908-7_1 EID: 2-s2.0-85120895456 ISSN: 10643745 19406029 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-85120895456&partnerID=MN8TOARS Suppression of YAP safeguards human na?ve pluripotency Journal: DEVELOPMENT Published: 30/11/2021 DOI: 10.1242/DEV.200988 WOSUID: WOS:000961966000013 URL: The people behind the papers – Anish Dattani and Ge Guo Journal: Development Cambridge Published: 30/11/2021 DOI: 10.1242/dev.201491 EID: 2-s2.0-85145742271 ISSN: 09501991 14779129 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-85145742271&partnerID=MN8TOARS Naive stem cell blastocyst model captures human embryo lineage segregation Journal: Cell Stem Cell Published: 30/04/2021 DOI: 10.1016/j.stem.2021.04.031 ISSN: 1934-5909 URL: http://dx.doi.org/10.1016/j.stem.2021.04.031 Human Naïve Epiblast Cells Possess Unrestricted Lineage Potential Journal: Cell Stem Cell Published: 31/03/2021 DOI: 10.1016/j.stem.2021.02.025 ISSN: 1934-5909 URL: http://dx.doi.org/10.1016/j.stem.2021.02.025 2020 Cancer-Related Mutations Are Not Enriched in Naive Human Pluripotent Stem Cells Journal: Cell Stem Cell Published: 30/11/2020 ISSN: 1934-5909 DOI: https://doi.org/10.1016/j.stem.2020.11.014 URL: http://www.sciencedirect.com/science/article/pii/S193459092030552X Trophectoderm Potency is Retained Exclusively in Human Naïve Cells Published: 04/02/2020 DOI: 10.1101/2020.02.04.933812 URL: https://doi.org/10.1101/2020.02.04.933812 2018 Efficient RNA-mediated reprogramming of human somatic cells to naïve pluripotency facilitated by tankyrase inhibition Journal: Biorxiv Published: 30/11/2018 DOI: 10.1101/636670 EID: 2-s2.0-85095640337 ISSN: 26928205 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-85095640337&partnerID=MN8TOARS The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells Journal: STEM CELL REPORTS Published: 30/11/2018 DOI: 10.1016/J.STEMCR.2019.03.014 WOSUID: WOS:000471007700007 URL: Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency Journal: STEM CELL REPORTS Published: 30/11/2018 DOI: 10.1016/J.STEMCR.2019.10.009 WOSUID: WOS:000502098700011 URL: Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblast Journal: Development Published: 01/01/2018 DOI: 10.1242/dev.158501 URL: https://doi.org/10.1242/dev.158501 2017 Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast Journal: DEVELOPMENT Published: 30/11/2017 DOI: 10.1242/DEV.158501 WOSUID: WOS:000424653300010 URL: Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast (vol 145, dev158501, 2018) Journal: DEVELOPMENT Published: 30/11/2017 DOI: 10.1242/DEV.169672 WOSUID: WOS:000443498200011 URL: Epigenetic resetting of human pluripotency Journal: Development Published: 01/08/2017 DOI: 10.1242/dev.146811 URL: https://doi.org/10.1242/dev.146811 2016 Epigenetic resetting of human pluripotency. Journal: Development Published: 30/11/2016 DOI: 10.1242/dev.146811 URL: https://www.ncbi.nlm.nih.gov/pubmed/28765214 Epigenetic resetting of human pluripotency (vol 144, pg 2748, 2017) Journal: Biorxiv Published: 30/11/2016 DOI: 10.1101/146712 EID: 2-s2.0-85095645245 ISSN: 26928205 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-85095645245&partnerID=MN8TOARS 2015 Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass. Journal: Stem Cell Reports Published: 30/11/2015 DOI: 10.1016/j.stemcr.2016.02.005 URL: http://www.ncbi.nlm.nih.gov/pubmed/26947977 2013 Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human (vol 158, pg 1254, 2014) Journal: CELL Published: 30/11/2013 DOI: 10.1016/J.CELL.2014.08.029 WOSUID: WOS:000343094200009 URL: 2011 Isolation of homozygous mutant mouse embryonic stem cells using a dual selection system Journal: Nucleic Acids Research Published: 30/11/2011 DOI: 10.1093/nar/gkr908 EID: 2-s2.0-84863143293 ISSN: 03051048 13624962 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-84863143293&partnerID=MN8TOARS 2010 A PiggyBac-based recessive screening method to identify pluripotency regulators. Journal: PLoS One Published: 30/11/2010 DOI: 10.1371/journal.pone.0018189 URL: http://www.ncbi.nlm.nih.gov/pubmed/21533166 Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1 Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Published: 30/11/2010 DOI: 10.1073/PNAS.1100893108 WOSUID: WOS:000296700000031 URL: 2009 A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency. Journal: Development Published: 30/11/2009 DOI: 10.1242/dev.052753 URL: http://www.ncbi.nlm.nih.gov/pubmed/20823062 Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency Journal: CELL STEM CELL Published: 30/11/2009 DOI: 10.1016/j.stem.2010.06.022 URL: 2008 Klf4 reverts developmentally programmed restriction of ground state pluripotency. Journal: Development Published: 30/11/2008 DOI: 10.1242/dev.030957 URL: http://www.ncbi.nlm.nih.gov/pubmed/19224983 Nanog is the gateway to the pluripotent ground state. Journal: Cell Published: 30/11/2008 DOI: 10.1016/j.cell.2009.07.039 URL: http://www.ncbi.nlm.nih.gov/pubmed/19703398 Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal. Journal: Cell Stem Cell Published: 30/11/2008 DOI: 10.1016/j.stem.2009.11.003 URL: http://www.ncbi.nlm.nih.gov/pubmed/19951688 2003 Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells Journal: Nature Published: 30/11/2003 DOI: 10.1038/nature02653 EID: 2-s2.0-3042531072 ISSN: 00280836 URL: https://www.scopus.com/inward/record.url?eid=2-s2.0-3042531072&partnerID=MN8TOARS