Dr Megan Stevens Research Fellow m.stevens2@exeter.ac.uk CLES Groups: Housden Group University profile 0000-0002-7474-6759 Publications Publications 2022 A repositioning screen using an FGFR2 splicing reporter reveals compounds that regulate epithelial-mesenchymal transitions and inhibit growth of prostate cancer xenografts. Journal: Molecular therapy. Methods & clinical development Published: 17/03/2022 PMID: 35402635 PMC: PMC8971352 DOI: 10.1016/j.omtm.2022.03.005 URL: https://europepmc.org/articles/PMC8971352 2021 A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties. Journal: Oncogenesis Published: 03/05/2021 PMID: 33941763 PMC: PMC8093282 DOI: 10.1038/s41389-021-00323-0 URL: https://europepmc.org/articles/PMC8093282 2019 Modulation of the Apoptosis Gene Bcl-x Function Through Alternative Splicing. Journal: Frontiers in genetics Published: 06/09/2019 PMID: 31552099 PMC: PMC6743414 DOI: 10.3389/fgene.2019.00804 URL: https://europepmc.org/articles/PMC6743414 The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo. Journal: RNA biology Published: 21/08/2019 PMID: 31432737 PMC: PMC6844573 DOI: 10.1080/15476286.2019.1652522 URL: https://europepmc.org/articles/PMC6844573 Modulation of Receptor Tyrosine Kinase Activity through Alternative Splicing of Ligands and Receptors in the VEGF-A/VEGFR Axis. Journal: Cells Published: 28/03/2019 PMID: 30925751 PMC: PMC6523102 DOI: 10.3390/cells8040288 URL: https://europepmc.org/articles/PMC6523102 2018 Anti-angiogenic isoform of vascular endothelial growth factor-A in cardiovascular and renal disease. Journal: Advances in clinical chemistry Published: 16/11/2018 PMID: 30612603 DOI: 10.1016/bs.acc.2018.10.001 URL: https://doi.org/10.1016/bs.acc.2018.10.001 Assessment of Kidney Function in Mouse Models of Glomerular Disease. Journal: Journal of visualized experiments : JoVE Published: 30/06/2018 PMID: 30010634 PMC: PMC6102025 DOI: 10.3791/57764 URL: https://europepmc.org/articles/PMC6102025 Modulation of VEGF-A Alternative Splicing as a Novel Treatment in Chronic Kidney Disease. Journal: Genes Published: 15/02/2018 PMID: 29462869 PMC: PMC5852594 DOI: 10.3390/genes9020098 URL: https://europepmc.org/articles/PMC5852594 2017 VEGF-A165 b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney. Journal: The Journal of physiology Published: 03/07/2017 PMID: 28574576 PMC: PMC5621502 DOI: 10.1113/jp274481 URL: https://europepmc.org/articles/PMC5621502 2016 Alternative Splicing in CKD. Journal: Journal of the American Society of Nephrology : JASN Published: 13/01/2016 PMID: 26763787 PMC: PMC4884122 DOI: 10.1681/asn.2015080908 URL: https://europepmc.org/articles/PMC4884122 2014 Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy. Journal: Journal of the American Society of Nephrology : JASN Published: 26/12/2014 PMID: 25542969 PMC: PMC4520162 DOI: 10.1681/asn.2014040350 URL: https://europepmc.org/articles/PMC4520162