Dr Ramy Ragheb Postdoctoral Research Fellow R.Ragheb@exeter.ac.uk Living System Institute - LSI University of Exeter Stocker Road Exeter EX4 4QD Groups: Hendrich Group University profile 0000-0001-5892-1767 Publications Publications 2025 The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements Published: 20/11/2025 DOI: 10.7554/elife.109280.1 URL: http://dx.doi.org/10.7554/elife.109280.1 2024 Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency. Journal: Molecular cell Published: 14/03/2024 PMID: 38490199 PMC: PMC7616059 DOI: 10.1016/j.molcel.2024.02.015 URL: https://europepmc.org/articles/PMC7616059 The Nucleosome Remodelling and Deacetylation complex coordinates the transcriptional response to lineage commitment in pluripotent cells. Journal: Biology open Published: 22/01/2024 PMID: 38149716 PMC: PMC10836651 DOI: 10.1242/bio.060101 URL: https://europepmc.org/articles/PMC10836651 2023 Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD. Journal: Nature structural & molecular biology Published: 28/09/2023 PMID: 37770717 PMC: PMC10643137 DOI: 10.1038/s41594-023-01095-4 URL: https://europepmc.org/articles/PMC10643137 2020 Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by the nucleosome remodelling and deacetylation complex. Journal: Stem cell research Published: 03/06/2020 PMID: 32535494 PMC: PMC7347010 DOI: 10.1016/j.scr.2020.101867 URL: https://europepmc.org/articles/PMC7347010 2017 Interplay between trauma and Pseudomonas entomophila infection in flies: a central role of the JNK pathway and of CrebA. Journal: Scientific reports Published: 24/11/2017 PMID: 29176735 PMC: PMC5701226 DOI: 10.1038/s41598-017-14969-7 URL: https://europepmc.org/articles/PMC5701226 Vorinostat and Mithramycin A in combination therapy as an interesting strategy for the treatment of Sézary T lymphoma: a transcriptomic approach. Journal: Archives of dermatological research Published: 10/07/2017 PMID: 28695331 DOI: 10.1007/s00403-017-1761-0 URL: https://amu.hal.science/hal-01595894