Dr Simone Antonio De Rose PDRF s.a.de-rose@exeter.ac.uk LSI LSI 3rd floor North office Groups: Gold Group University profile https://orcid.org/0000-0001-5345-1014 Publications Publications 2025 Functional and structural insights into a thermostable (S)-selective amine transaminase and its improved substrate scope by protein engineering Journal: Applied Microbiology and Biotechnology Published: 12/08/2025 DOI: 10.1007/s00253-025-13536-9 URL: https://doi.org/10.1007/s00253-025-13536-9 2024 Editorial: 13th international congress on extremophiles: from extremophilic biomolecules and microorganisms to biotechnological and sustainable applications. Journal: Frontiers in microbiology Published: 15/05/2024 LENSID: 051-695-519-483-103 PMID: 38812682 PMC: pmc11133862 DOI: 10.3389/fmicb.2024.1414760 URL: https://www.lens.org/051-695-519-483-103 2023 Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus. Journal: Frontiers in Microbiology Published: 16/11/2023 DOI: 10.3389/fmicb.2023.1267570 ISSN: 1664-302X URL: http://dx.doi.org/10.3389/fmicb.2023.1267570 2021 Production of the Extremolyte Cyclic 2,3-Diphosphoglycerate Using Thermus thermophilus as a Whole-Cell Factory Journal: Frontiers in Catalysis Published: 20/12/2021 DOI: 10.3389/fctls.2021.803416 ISSN: 2673-7841 URL: http://dx.doi.org/10.3389/fctls.2021.803416 Biochemical and Structural Characterisation of a Novel D-Lyxose Isomerase From the Hyperthermophilic Archaeon Thermofilum sp. Journal: Frontiers in Bioengineering and Biotechnology Published: 06/08/2021 DOI: 10.3389/fbioe.2021.711487 ISSN: 2296-4185 URL: http://dx.doi.org/10.3389/fbioe.2021.711487 2020 A ‘Split-Gene’ Transketolase From the Hyper-Thermophilic Bacterium Carboxydothermus hydrogenoformans: Structure and Biochemical Characterization Journal: Frontiers in Microbiology Published: 30/10/2020 DOI: 10.3389/fmicb.2020.592353 ISSN: 1664-302X URL: http://dx.doi.org/10.3389/fmicb.2020.592353 Structural insights into the NAD+-dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD+ ternary complex of the Chaetomium thermophilum enzyme Journal: Journal of Structural Biology Published: 30/09/2020 DOI: 10.1016/j.jsb.2020.107657 ISSN: 1047-8477 URL: http://dx.doi.org/10.1016/j.jsb.2020.107657 DETERGENT COMPOSITION Published: 28/05/2020 LENSID: 166-418-876-033-981 URI: lens.org/166-418-876-033-981 PAT: WO 2020/104159 A1 URL: https://www.lens.org/166-418-876-033-981 Using enzyme cascades in biocatalysis: Highlight on transaminases and carboxylic acid reductases Journal: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics Published: 31/01/2020 DOI: 10.1016/j.bbapap.2019.140322 URL: https://doi.org/10.1016/j.bbapap.2019.140322 2019 Detergent compositions with lipase and biosurfactant Published: 03/09/2019 LENSID: 117-244-506-295-832 URI: lens.org/117-244-506-295-832 PAT: US 10400197 B2 URL: https://www.lens.org/117-244-506-295-832 2018 IMPROVED WASH COMPOSITIONS Published: 23/08/2018 LENSID: 092-439-782-340-42X URI: lens.org/092-439-782-340-42X PAT: US 2018/0237729 A1 URL: https://www.lens.org/092-439-782-340-42X LIQUID DETERGENCY COMPOSITION COMPRISING PROTEASE AND NON-PROTEASE ENZYME Published: 04/07/2018 LENSID: 104-407-175-350-447 URI: lens.org/104-407-175-350-447 PAT: EP 3341460 A1 URL: https://www.lens.org/104-407-175-350-447 2017 New thermophilic α/β class epoxide hydrolases found in metagenomes from hot environments Journal: Frontiers in Bioengineering and Biotechnology Published: 30/11/2017 DOI: 10.3389/fbioe.2018.00144 EID: 2-s2.0-85055746218 URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-85055746218&partnerID=MN8TOARS Thermostable Isomerase Processes for Biotechnology Published: 27/08/2017 LENSID: 041-073-144-232-084 URL: https://www.lens.org/041-073-144-232-084 PROCESS TO MANUFACTURE CROSS-LINKED ENZYME AGGREGATES Published: 27/04/2017 LENSID: 134-042-207-452-368 URI: lens.org/134-042-207-452-368 PAT: WO 2017/036916 A8 URL: https://www.lens.org/134-042-207-452-368 LIQUID DETERGENCY COMPOSITION COMPRISING LIPASE AND PROTEASE Published: 09/03/2017 LENSID: 154-446-779-986-468 URI: lens.org/154-446-779-986-468 PAT: WO 2017/036917 A1 URL: https://www.lens.org/154-446-779-986-468 Stabilization of a Lipolytic Enzyme for Commercial Application Journal: Catalysts Published: 28/02/2017 DOI: 10.3390/catal7030091 URL: http://www.mdpi.com/2073-4344/7/3/91