
Publications
2023
Cancer-associated fibroblasts influence Wnt/PCP signaling in gastric cancer cells by cytoneme-based dissemination of ROR2
Journal:
Proceedings of the National Academy of Sciences
Published:
26/09/2023
DOI: 10.1073/pnas.2217612120
URL: https://doi.org/10.1073/pnas.2217612120
Wnt-7a-positive dendritic cytonemes induce synaptogenesis in cortical neurons.
Published: 17/02/2023DOI: 10.1101/2023.02.17.528927
URL: https://doi.org/10.1101/2023.02.17.528927
2022
The scaffolding protein Flot2 promotes cytoneme-based transport of Wnt3 in gastric cancer
Journal:
eLife
Published:
30/08/2022
DOI: 10.7554/eLife.77376
URL: https://doi.org/10.7554/eLife.77376
Vertebrate Wnt5a – At the crossroads of cellular signalling
Journal:
Seminars in Cell & Developmental Biology
Published:
30/04/2022
DOI: 10.1016/j.semcdb.2021.10.002
URL: https://doi.org/10.1016/j.semcdb.2021.10.002
Cancer-associated fibroblast-derived ROR2 induces WNT/PCP activation and polarized migration in receiving gastric cancer cells
Published: 08/04/2022DOI: 10.1101/2022.04.07.487474
URL: https://doi.org/10.1101/2022.04.07.487474
Cytoneme-mediated transport of active Wnt5b/Ror2 complexes in zebrafish gastrulation
Published: 08/04/2022DOI: 10.1101/2022.04.07.487468
URL: https://doi.org/10.1101/2022.04.07.487468
The scaffolding protein Flot2 regulates cytoneme-based transport of Wnt3 in gastric cancer
Published: 08/01/2022DOI: 10.1101/2022.01.07.475396
URL: https://doi.org/10.1101/2022.01.07.475396
2021
A combined human in silico and CRISPR/Cas9-mediated in vivo zebrafish based approach for supporting gene target validation in early drug discovery
Published: 14/09/2021DOI: 10.1101/2021.09.14.460241
URL: https://doi.org/10.1101/2021.09.14.460241
Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling
Journal:
Nature Communications
Published:
06/04/2021
DOI: 10.1038/s41467-021-22393-9
URL: https://doi.org/10.1038/s41467-021-22393-9
2020
Vangl2 regulates the dynamics of Wnt cytonemes in vertebrates
Published: 23/12/2020DOI: 10.1101/2020.12.23.424142
URL: https://doi.org/10.1101/2020.12.23.424142
Delay-driven oscillations via Axin2 feedback in the Wnt/β-catenin signalling pathway
Journal:
Journal of Theoretical Biology
Published:
30/11/2020
DOI: 10.1016/j.jtbi.2020.110458
URL: https://doi.org/10.1016/j.jtbi.2020.110458
Introduction: in vivo cell biology in zebrafish.
Journal:
Histochemistry and cell biology
Published:
29/10/2020
PMID: 33118079
DOI: 10.1007/s00418-020-01931-4
URL: https://doi.org/10.1007/s00418-020-01931-4
Studying molecular interactions in the intact organism: fluorescence correlation spectroscopy in the living zebrafish embryo.
Journal:
Histochemistry and cell biology
Published:
16/10/2020
PMID: 33067656
PMC: PMC7609432
DOI: 10.1007/s00418-020-01930-5
URL: https://europepmc.org/articles/PMC7609432
Development of the electric organ in embryos and larvae of the knifefish, Brachyhypopomus gauderio
Journal:
Developmental Biology
Published:
30/09/2020
DOI: 10.1016/j.ydbio.2020.06.010
URL: https://doi.org/10.1016/j.ydbio.2020.06.010
Modeling of Wnt-mediated tissue patterning in vertebrate embryogenesis
Journal:
PLOS Computational Biology
Published:
24/06/2020
DOI: 10.1371/journal.pcbi.1007417
URL: https://doi.org/10.1371/journal.pcbi.1007417
2019
Cytonemes in development
Journal:
Current Opinion in Genetics & Development
Published:
31/07/2019
DOI: 10.1016/j.gde.2019.06.005
ISSN: 0959-437X
URL: http://dx.doi.org/10.1016/j.gde.2019.06.005
Mechanisms of intercellular Wnt transport
Journal:
Development
Published:
15/05/2019
DOI: 10.1242/dev.176073
URL: https://doi.org/10.1242/dev.176073
2018
From top to bottom: Cell polarity in Hedgehog and Wnt trafficking
Journal:
BMC Biology
Published:
30/11/2018
DOI: 10.1186/s12915-018-0511-x
URL: https://doi.org/10.1186/s12915-018-0511-x
Emerging role of contact-mediated cell communication in tissue development and diseases
Journal:
Histochemistry and Cell Biology
Published:
25/11/2018
DOI: 10.1007/s00418-018-1732-3
URL: https://doi.org/10.1007/s00418-018-1732-3
Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates.
Journal:
eLife
Published:
30/06/2018
PMID: 30060804
DOI: 10.7554/elife.36953
URL: http://europepmc.org/abstract/med/30060804
Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms.
Journal:
Science (New York, N.Y.)
Published:
31/03/2018
PMID: 29674564
DOI: 10.1126/science.aaq1392
URL: http://europepmc.org/abstract/med/29674564
The function of endocytosis in Wnt signaling.
Journal:
Cellular and molecular life sciences : CMLS
Published:
28/02/2018
PMID: 28913633
PMC: PMC5809524
DOI: 10.1007/s00018-017-2654-2
URL: http://europepmc.org/abstract/med/28913633
2016
Secreted frizzled-related protein 2 (sFRP2) redirects non-canonical Wnt signaling from Fz7 to Ror2 during vertebrate gastrulation.
Published: 31/03/2016PMID: 27129770
URL: http://europepmc.org/abstract/med/27129770
2015
Role of cytonemes in Wnt transport.
Published: 31/12/2015PMID: 26823607
URL: http://europepmc.org/abstract/med/26823607
Photolithographic patterning of 3D-formed polycarbonate films for targeted cell guiding.
Published: 31/03/2015PMID: 25787094
DOI: 10.1002/adma.201500426
URL: http://europepmc.org/abstract/med/25787094
2014
Filopodia-based Wnt transport during vertebrate tissue patterning.
Published: 30/11/2014PMID: 25556612
DOI: 10.1038/ncomms6846
URL: http://europepmc.org/abstract/med/25556612
Tyrosine phosphorylation of LRP6 by Src and Fer inhibits Wnt/β-catenin signalling.
Published: 30/11/2014PMID: 25391905
DOI: 10.15252/embr.201439644
URL: http://europepmc.org/abstract/med/25391905
2013
Endocytosis of Fgf8 is a double-stage process and regulates spreading and signaling.
Published: 30/11/2013PMID: 24466061
PMC: PMC3896487
DOI: 10.1371/journal.pone.0086373
URL: http://europepmc.org/abstract/med/24466061
In vivo analysis of formation and endocytosis of the Wnt/beta-Catenin signaling complex in zebrafish embryos.
Journal:
Journal of cell science
Published:
30/11/2013
DOI: 10.1242/jcs.148767
URL:
Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates
Published: 30/11/2013DOI: 10.1186/1741-7007-12-13
EID: 2-s2.0-84899141018
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84899141018&partnerID=MN8TOARS
2012
Brain on the stage – Spotlight on nervous system development in zebrafish: EMBO practical course, KIT, Sept. 2013
Published: 30/11/2012DOI: 10.1186/1749-8104-8-23
EID: 2-s2.0-84890403284
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84890403284&partnerID=MN8TOARS
Building the gateway to consciousness-about the development of the thalamus.
Published: 30/11/2012PMID: 23760777
PMC: PMC3671175
DOI: 10.3389/fnins.2013.00094
URL: http://europepmc.org/abstract/med/23760777
Micropatterned superhydrophobic structures for the simultaneous culture of multiple cell types and the study of cell-cell communication
Published: 30/11/2012DOI: 10.1016/j.biomaterials.2012.11.034
EID: 2-s2.0-84871095068
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84871095068&partnerID=MN8TOARS
Neurogenesis in zebrafish – from embryo to adult
Published: 30/11/2012DOI: 10.1186/1749-8104-8-3
EID: 2-s2.0-84874007223
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84874007223&partnerID=MN8TOARS
2011
The tale of the three brothers – Shh, Wnt, and Fgf during development of the thalamus
Published: 30/11/2011DOI: 10.3389/fnins.2012.00076
EID: 2-s2.0-84862228793
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84862228793&partnerID=MN8TOARS
Wnt3 and Wnt3a are required for induction of the mid-diencephalic organizer in the caudal forebrain
Published: 30/11/2011DOI: 10.1186/1749-8104-7-12
EID: 2-s2.0-84859189794
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84859189794&partnerID=MN8TOARS
2010
Lhx2 and Lhx9 determine neuronal differentiation and compartition in the caudal forebrain by regulating Wnt signaling
Published: 30/11/2010DOI: 10.1371/journal.pbio.1001218
EID: 2-s2.0-84855176609
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84855176609&partnerID=MN8TOARS
2009
Building a bridal chamber: Development of the thalamus
Published: 30/11/2009DOI: 10.1016/j.tins.2010.05.003
EID: 2-s2.0-77955279065
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-77955279065&partnerID=MN8TOARS
Molecular pathways controlling development of thalamus and hypothalamus: From neural specification to circuit formation
Published: 30/11/2009DOI: 10.1523/JNEUROSCI.4499-10.2010
EID: 2-s2.0-78149482636
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-78149482636&partnerID=MN8TOARS
Neural Patterning: Midbrain-Hindbrain Boundary
Published: 30/11/2009DOI: 10.1016/B978-008045046-9.01066-4
EID: 2-s2.0-84882822385
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84882822385&partnerID=MN8TOARS
Ontogenesis of the brain: The development of the thalamus – The gateway to consciousness | Ontogenese des Gehirns Die Entwicklung des Thalamus -das Tor zum Bewusstsein
Published: 30/11/2009EID: 2-s2.0-77958039986
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-77958039986&partnerID=MN8TOARS
Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway
Published: 30/11/2009DOI: 10.1038/nn.2662
EID: 2-s2.0-78049287669
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-78049287669&partnerID=MN8TOARS
2008
Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules
Published: 30/11/2008DOI: 10.1038/nature08391
EID: 2-s2.0-70349453919
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-70349453919&partnerID=MN8TOARS
Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus
Published: 30/11/2008DOI: 10.1073/pnas.0910894106
EID: 2-s2.0-73949152966
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-73949152966&partnerID=MN8TOARS
2006
Early developmental specification of the thyroid gland depends on han-expressing surrounding tissue and on FGF signals
Published: 30/11/2006DOI: 10.1242/dev.02872
EID: 2-s2.0-34547483655
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-34547483655&partnerID=MN8TOARS
Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon
Published: 30/11/2006DOI: 10.1242/dev.001461
EID: 2-s2.0-34848847165
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-34848847165&partnerID=MN8TOARS
Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries
Published: 30/11/2006DOI: 10.1016/j.ydbio.2006.08.022
EID: 2-s2.0-33846258014
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-33846258014&partnerID=MN8TOARS
2005
Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon
Published: 30/11/2005DOI: 10.1242/dev.02248
EID: 2-s2.0-32344446690
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-32344446690&partnerID=MN8TOARS
2003
Zebrafish fgfr1 is a member of the fgf8 synexpression group and is required for fgf8 signalling at the midbrain-hindbrain boundary.
Published: 30/11/2003EID: 2-s2.0-3543006549
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-3543006549&partnerID=MN8TOARS
Endocytosis controls spreading and effective signaling range of Fgf8 protein
Published: 30/11/2003DOI: 10.1016/j.cub.2004.09.084
EID: 2-s2.0-6944255474
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-6944255474&partnerID=MN8TOARS
Zebrafish fgfr1 is a member of the fgf8 synexpression group and is required for fgf8 signalling at the midbrain-hindbrain boundary
Published: 30/11/2003EID: 2-s2.0-3543006549
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-3543006549&partnerID=MN8TOARS
2002
Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon
Published: 30/11/2002DOI: 10.1242/dev.00683
EID: 2-s2.0-0142181010
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0142181010&partnerID=MN8TOARS
Erratum: Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon (Development vol. 130 (4881-4893))
Published: 30/11/2002EID: 2-s2.0-0242719723
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0242719723&partnerID=MN8TOARS
Integrity of the Midbrain Region Is Required to Maintain the Diencephalic-Mesencephalic Boundary in Zebrafish no isthmus/pax2.1 Mutants
Published: 30/11/2002DOI: 10.1002/dvdy.10384
EID: 2-s2.0-0142222325
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0142222325&partnerID=MN8TOARS
2001
A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines.
Published: 30/11/2001EID: 2-s2.0-0036333606
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036333606&partnerID=MN8TOARS
A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines
Published: 30/11/2001EID: 2-s2.0-0036333606
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036333606&partnerID=MN8TOARS
2000
Morpholino-induced knockdown of zebrafish engrailed genes eng2 and eng3 reveals redundant and unique functions in midbrain-hindbrain boundary development
Published: 30/11/2000DOI: 10.1002/gene.1047
EID: 2-s2.0-0034908357
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0034908357&partnerID=MN8TOARS