Dr Vicki Gold Associate Professor V.A.M.Gold@exeter.ac.uk Living Systems Institute/ Systems Block Groups: Gold Group University profile 0000-0002-6908-0745 Publications Publications 2024 Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail Published: 09/12/2024 DOI: 10.1101/2024.12.09.627619 URL: https://doi.org/10.1101/2024.12.09.627619 Towards a molecular picture of the archaeal cell surface Journal: Nature Communications Published: 29/11/2024 DOI: 10.1038/s41467-024-53986-9 URL: https://doi.org/10.1038/s41467-024-53986-9 Unusual cell surfaces, pili and archaella of Thermoplasmatales archaea investigated by cryoEM Published: 25/10/2024 DOI: 10.21203/rs.3.rs-5269562/v1 URL: https://doi.org/10.21203/rs.3.rs-5269562/v1 Structure, Biology, and Applications of Filamentous Bacteriophages Journal: Cold Spring Harbor Protocols Published: 31/07/2024 DOI: 10.1101/pdb.over107754 URL: https://doi.org/10.1101/pdb.over107754 Factors of prescribing phage therapy among UK healthcare professionals: Evidence from conjoint experiment and interviews Journal: PLOS ONE Published: 07/05/2024 DOI: 10.1371/journal.pone.0303056 URL: https://doi.org/10.1371/journal.pone.0303056 2023 CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state Journal: Nature Microbiology Published: 14/09/2023 DOI: 10.1038/s41564-023-01469-w URL: https://doi.org/10.1038/s41564-023-01469-w CryoEM reveals the structure of an archaeal pilus involved in twitching motility. Published: 16/08/2023 DOI: 10.21203/rs.3.rs-3245295/v1 URL: https://doi.org/10.21203/rs.3.rs-3245295/v1 Phage therapy and the public: Increasing awareness essential to widespread use Journal: PLOS ONE Published: 18/05/2023 DOI: 10.1371/journal.pone.0285824 URL: https://doi.org/10.1371/journal.pone.0285824 Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly Journal: Nature Communications Published: 11/05/2023 DOI: 10.1038/s41467-023-37915-w URL: https://doi.org/10.1038/s41467-023-37915-w Cryo-electron tomography of C. elegans mitochondria reveals how the ATP synthase dimer interface shapes crista membranes Published: 03/02/2023 DOI: 10.1101/2023.02.02.526626 URL: https://doi.org/10.1101/2023.02.02.526626 Cryo-electron tomography ofC. elegansmitochondria reveals how the ATP synthase dimer interface shapes crista membranes Published: 03/02/2023 DOI: 10.1101/2023.02.02.526626 URL: https://doi.org/10.1101/2023.02.02.526626 The consequence of ATP synthase dimer angle on mitochondrial morphology studied by cryo-electron tomography Published: 03/02/2023 DOI: 10.1101/2023.02.02.526626 URL: https://doi.org/10.1101/2023.02.02.526626 2022 Electron cryo-microscopy reveals the structure of the archaeal thread filament Journal: Nature Communications Published: 01/12/2022 DOI: 10.1038/s41467-022-34652-4 URL: https://doi.org/10.1038/s41467-022-34652-4 Cryo-electron microscopy of the f1 filamentous phage reveals a new paradigm in viral infection and assembly Published: 04/11/2022 DOI: 10.1101/2022.11.03.514279 URL: https://doi.org/10.1101/2022.11.03.514279 Sample preparation in single particle cryo-EM: general discussion. Journal: Faraday discussions Published: 31/10/2022 PMID: 36278863 DOI: 10.1039/d2fd90059a URL: http://europepmc.org/abstract/med/36278863 Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius Published: 07/10/2022 DOI: 10.1101/2022.10.07.511299 URL: https://doi.org/10.1101/2022.10.07.511299 INTERACTION OF THE PERIPLASMIC CHAPERONE SURA WITH THE INNER MEMBRANE PROTEIN SECRETION (SEC) MACHINERY Published: 14/09/2022 DOI: 10.1101/2022.09.14.507990 URL: https://doi.org/10.1101/2022.09.14.507990 INTERACTION OF THE PERIPLASMIC CHAPERONE SURA WITH THE INNER MEMBRANE PROTEIN SECRETION (SEC) MACHINERY. Published: 14/09/2022 DOI: 10.1101/2022.09.14.507990 URL: https://doi.org/10.1101/2022.09.14.507990 In situ structure of a dimeric hibernating ribosome from a eukaryotic intracellular pathogen Published: 30/04/2022 DOI: 10.1101/2022.04.29.490036 URL: https://doi.org/10.1101/2022.04.29.490036 Donor strand complementation, isopeptide bonds and glycosylation reinforce highly resilient archaeal thread filaments Published: 26/04/2022 DOI: 10.1101/2022.04.26.489512 URL: https://doi.org/10.1101/2022.04.26.489512 An archaellum filament composed of two alternating subunits Journal: Nature Communications Published: 07/02/2022 DOI: 10.1038/s41467-022-28337-1 URL: https://doi.org/10.1038/s41467-022-28337-1 2021 Pushing the limits in single particle cryo-EM: general discussion Journal: Faraday Discussions Published: 30/11/2021 DOI: 10.1039/D2FD90063G URL: https://doi.org/10.1039/D2FD90063G New insights into the architecture and dynamics of archaella Published: 01/10/2021 DOI: 10.1101/2021.10.01.462426 URL: https://doi.org/10.1101/2021.10.01.462426 CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage Published: 21/07/2021 DOI: 10.1101/2021.07.20.453082 URL: https://doi.org/10.1101/2021.07.20.453082 Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health Journal: Journal of Cell Science Published: 01/07/2021 DOI: 10.1242/jcs.258399 URL: https://doi.org/10.1242/jcs.258399 Maintenance of Complex I and respiratory super-complexes by NDUF-11 is essential for respiratory function, mitochondrial structure and health in C. elegans Published: 06/01/2021 DOI: 10.1101/2021.01.06.425530 URL: https://doi.org/10.1101/2021.01.06.425530 Maintenance of Complex I and respiratory super-complexes by NDUF-11 is essential for respiratory function, mitochondrial structure and health inC. elegans Published: 06/01/2021 DOI: 10.1101/2021.01.06.425530 URL: https://doi.org/10.1101/2021.01.06.425530 2020 Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium Journal: Nature Communications Published: 30/11/2020 DOI: 10.1038/s41467-020-15650-w URL: https://doi.org/10.1038/s41467-020-15650-w Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium. Journal: Nature Communications Published: 06/05/2020 DOI: 10.1038/s41467-020-15650-w URL: https://doi.org/10.1038/s41467-020-15650-w 2019 Architecture and modular assembly of Sulfolobus S-layers revealed by electron cryotomography Journal: Proceedings of the National Academy of Sciences Published: 10/12/2019 DOI: 10.1073/pnas.1911262116 URL: https://doi.org/10.1073/pnas.1911262116 Architecture and modular assembly of Sulfolobus S-layers revealed by electron cryotomography. Journal: Proceedings of the National Academy of Sciences of the United States of America Published: 25/11/2019 PMID: 31767763 DOI: 10.1073/pnas.1911262116 URL: https://doi.org/10.1073/pnas.1911262116 Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis Published: 27/03/2019 DOI: 10.1101/589077 URL: https://doi.org/10.1101/589077 2018 Twitch or swim: towards the understanding of prokaryotic motion based on the type IV pilus blueprint Journal: Biological Chemistry Published: 01/06/2018 DOI: 10.1515/hsz-2018-0157 ISSN: 1437-4315 URL: 2017 The ER morphology-regulating lunapark protein induces the formation of stacked bilayer discs Journal: Life Science Alliance Published: 30/11/2017 DOI: 10.26508/lsa.201700014 EID: 2-s2.0-85053830183 URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-85053830183&partnerID=MN8TOARS Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo‐tomography Journal: EMBO reports Published: 30/09/2017 DOI: 10.15252/embr.201744261 URL: https://doi.org/10.15252/embr.201744261 2016 Analysis of Mitochondrial Membrane Protein Complexes by Electron Cryo-tomography. Published: 30/11/2016 PMID: 28276027 DOI: 10.1007/978-1-4939-6824-4_19 URL: http://europepmc.org/abstract/med/28276027 Recent progress in structure and dynamics of dual-membrane-spanning bacterial nanomachines. Published: 31/07/2016 PMID: 26995496 DOI: 10.1016/j.sbi.2016.03.001 URL: http://europepmc.org/abstract/med/26995496 Topology and Structure/Function Correlation of Ring- and Gate-forming Domains in the Dynamic Secretin Complex of Thermus thermophilus. Published: 30/06/2016 PMID: 27226590 DOI: 10.1074/jbc.m116.724153 URL: http://europepmc.org/abstract/med/27226590 Protein Import by the Mitochondrial Presequence Translocase in the Absence of a Membrane Potential. Published: 29/02/2016 PMID: 26827728 DOI: 10.1016/j.jmb.2016.01.020 URL: http://europepmc.org/abstract/med/26827728 2014 Structure of a type IV pilus machinery in the open and closed state. Published: 30/11/2014 PMID: 25997099 PMC: PMC4463427 DOI: 10.7554/elife.07380 URL: http://europepmc.org/abstract/med/25997099 Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC. Published: 31/03/2014 PMID: 24550475 PMC: PMC3977283 DOI: 10.1073/pnas.1315901111 URL: http://europepmc.org/abstract/med/24550475 2013 A cell model for the initial phase of sporadic Alzheimer’s disease. Published: 30/11/2013 PMID: 24898661 DOI: 10.3233/jad-140381 URL: http://europepmc.org/abstract/med/24898661 Visualization of ATP synthase dimers in mitochondria by electron cryo-tomography. Published: 30/11/2013 PMID: 25285856 PMC: PMC4828066 DOI: 10.3791/51228 URL: http://europepmc.org/abstract/med/25285856 Visualizing active membrane protein complexes by electron cryotomography. Published: 30/11/2013 PMID: 24942077 PMC: PMC4090714 DOI: 10.1038/ncomms5129 URL: http://europepmc.org/abstract/med/24942077 The dynamic action of SecA during the initiation of protein translocation. Published: 31/01/2013 PMID: 23126322 PMC: PMC3685266 DOI: 10.1042/bj20121314 URL: http://europepmc.org/abstract/med/23126322 2012 Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex. Published: 30/11/2012 PMID: 23209305 PMC: PMC3518217 DOI: 10.1083/jcb.201205191 URL: http://europepmc.org/abstract/med/23209305 2011 Structure of the SecY complex unlocked by a preprotein mimic. Published: 31/12/2011 PMID: 22576621 PMC: PMC3333808 DOI: 10.1016/j.celrep.2011.11.003 URL: http://europepmc.org/abstract/med/22576621 The oligomeric state and arrangement of the active bacterial translocon. Published: 31/01/2011 PMID: 21056980 PMC: PMC3039378 DOI: 10.1074/jbc.m110.175638 URL: http://europepmc.org/abstract/med/21056980 2010 The action of cardiolipin on the bacterial translocon. Published: 31/05/2010 PMID: 20479269 PMC: PMC2890433 DOI: 10.1073/pnas.0914680107 URL: http://europepmc.org/abstract/med/20479269 2009 Energy transduction in protein transport and the ATP hydrolytic cycle of SecA. Published: 28/02/2009 PMID: 19273842 PMC: PMC2653558 DOI: 10.1073/pnas.0809592106 URL: http://europepmc.org/abstract/med/19273842 2007 A large conformational change couples the ATP binding site of SecA to the SecY protein channel. Published: 30/11/2007 PMID: 17964601 DOI: 10.1016/j.jmb.2007.09.086 URL: http://europepmc.org/abstract/med/17964601 Allosteric regulation of SecA: magnesium-mediated control of conformation and activity. Published: 31/05/2007 PMID: 17416585 DOI: 10.1074/jbc.m702066200 URL: http://europepmc.org/abstract/med/17416585 2006 Structure and function of the bacterial Sec translocon. Published: 30/11/2006 PMID: 17710643 DOI: 10.1080/09687680701416570 URL: http://europepmc.org/abstract/med/17710643 1999 The SecA ATPase reaction cycle and its consequence in protein translocation. Published: 30/11/1999 OTHER-ID: 446153 URL: http://europepmc.org/theses/ETH/446153