Dr Zhili Ren Postdoctoral Research Fellow Z.Ren@exeter.ac.uk CLES Groups: Smith Group University profile 0000-0002-6115-050X Publications Publications 2023 Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells Journal: Stem Cells Published: 15/06/2023 DOI: 10.1093/stmcls/sxad006 ISSN: 1066-5099 URL: http://dx.doi.org/10.1093/stmcls/sxad006 2022 Insulin Directs Dichotomous Translational Regulation to Control Human Pluripotent Stem Cell Survival, Proliferation and Pluripotency Journal: International Journal of Biological Sciences Published: 30/04/2022 DOI: 10.7150/ijbs.71199 ISSN: 1449-2288 URL: http://dx.doi.org/10.7150/ijbs.71199 Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells Journal: Stem Cell Research & Therapy Published: 28/02/2022 DOI: 10.1186/s13287-022-02799-y ISSN: 1757-6512 URL: http://dx.doi.org/10.1186/s13287-022-02799-y 2021 Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells Journal: Cell Reports Published: 31/10/2021 DOI: 10.1016/j.celrep.2021.110063 ISSN: 2211-1247 URL: http://dx.doi.org/10.1016/j.celrep.2021.110063 Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells Journal: Cell Death & Disease Published: 31/10/2021 DOI: 10.1038/s41419-021-04395-z ISSN: 2041-4889 URL: http://dx.doi.org/10.1038/s41419-021-04395-z Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells Journal: Stem Cell Research & Therapy Published: 31/05/2021 DOI: 10.1186/s13287-021-02426-2 ISSN: 1757-6512 URL: http://dx.doi.org/10.1186/s13287-021-02426-2 2020 Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal: Stem Cell Reports Published: 30/11/2020 DOI: 10.1016/j.stemcr.2020.10.008 ISSN: 2213-6711 URL: http://dx.doi.org/10.1016/j.stemcr.2020.10.008 Novel venom-based peptides (P13 and its derivative—M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways Journal: Stem Cell Research & Therapy Published: 31/05/2020 DOI: 10.1186/s13287-020-01766-9 ISSN: 1757-6512 URL: http://dx.doi.org/10.1186/s13287-020-01766-9 Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal: International Journal of Biological Sciences Published: 31/01/2020 DOI: 10.7150/ijbs.44414 ISSN: 1449-2288 URL: http://dx.doi.org/10.7150/ijbs.44414 2019 Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells Journal: Cell Reports Published: 30/11/2019 DOI: 10.1016/j.celrep.2019.11.047 ISSN: 2211-1247 URL: http://dx.doi.org/10.1016/j.celrep.2019.11.047 Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal: Stem Cell Reports Published: 31/07/2019 DOI: 10.1016/j.stemcr.2019.06.003 ISSN: 2213-6711 URL: http://dx.doi.org/10.1016/j.stemcr.2019.06.003 2018 Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells Journal: Stem Cell Reports Published: 30/11/2018 DOI: 10.1016/j.stemcr.2018.10.023 ISSN: 2213-6711 URL: http://dx.doi.org/10.1016/j.stemcr.2018.10.023 The Suppression of Medium Acidosis Improves the Maintenance and Differentiation of Human Pluripotent Stem Cells at High Density in Defined Cell Culture Medium Journal: International Journal of Biological Sciences Published: 31/03/2018 DOI: 10.7150/ijbs.24681 ISSN: 1449-2288 URL: http://dx.doi.org/10.7150/ijbs.24681