Prof Austin Smith Director of Living Systems Institute Austin.Smith@exeter.ac.uk CLES Groups: Smith Group University profile 0000-0002-3029-4682 Publications Publications 2020 Disabling de novo DNA methylation in embryonic stem cells allows an illegitimate fate trajectory Published: 20/12/2020 DOI: 10.1101/2020.12.20.423404 URL: https://doi.org/10.1101/2020.12.20.423404 Cancer-Related Mutations Are Not Enriched in Naive Human Pluripotent Stem Cells Journal: Cell Stem Cell Published: 30/11/2020 ISSN: 1934-5909 DOI: https://doi.org/10.1016/j.stem.2020.11.014 URL: http://www.sciencedirect.com/science/article/pii/S193459092030552X Embryonic stem cells commit to differentiation by symmetric divisions following a variable lag period Published: 18/06/2020 DOI: 10.1101/2020.06.17.157578 URL: https://doi.org/10.1101/2020.06.17.157578 Trophectoderm Potency is Retained Exclusively in Human Naïve Cells Published: 04/02/2020 DOI: 10.1101/2020.02.04.933812 URL: https://doi.org/10.1101/2020.02.04.933812 Zfp281 orchestrates interconversion of pluripotent states by engaging Ehmt1 and Zic2 Journal: The EMBO Journal Published: 15/01/2020 DOI: 10.15252/embj.2019102591 URL: https://doi.org/10.15252/embj.2019102591 2019 Microfluidic platform for 3D cell culture with live imaging and clone retrieval Journal: Lab on a Chip Published: 30/11/2019 DOI: 10.1039/D0LC00165A URL: https://doi.org/10.1039/D0LC00165A Capacitation of human naïve pluripotent stem cells for multi-lineage differentiation Journal: Development Published: 01/04/2019 DOI: 10.1242/dev.172916 URL: https://doi.org/10.1242/dev.172916 Defined conditions for propagation and manipulation of mouse embryonic stem cells Journal: Development Published: 15/03/2019 DOI: 10.1242/dev.173146 URL: https://doi.org/10.1242/dev.173146 2018 A common molecular logic determines embryonic stem cell self‐renewal and reprogramming Journal: The EMBO Journal Published: 31/12/2018 DOI: 10.15252/embj.2018100003 URL: https://doi.org/10.15252/embj.2018100003 Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development Journal: Development Published: 01/11/2018 DOI: 10.1242/dev.167833 URL: https://doi.org/10.1242/dev.167833 Negative feedback via RSK modulates Erk‐dependent progression from naïve pluripotency Journal: EMBO reports Published: 31/07/2018 DOI: 10.15252/embr.201745642 URL: https://doi.org/10.15252/embr.201745642 Pluripotency Deconstructed Journal: Development, Growth & Differentiation Published: 23/01/2018 DOI: 10.1111/dgd.12419 URL: https://doi.org/10.1111/dgd.12419 Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblast Journal: Development Published: 01/01/2018 DOI: 10.1242/dev.158501 URL: https://doi.org/10.1242/dev.158501 2017 Esrrb Complementation Rescues Development of Nanog-Null Germ Cells. Journal: Cell Rep Published: 30/11/2017 DOI: 10.1016/j.celrep.2017.12.060 URL: https://www.ncbi.nlm.nih.gov/pubmed/29320730 Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity. Journal: EMBO J Published: 30/11/2017 DOI: 10.15252/embj.201798133 URL: https://www.ncbi.nlm.nih.gov/pubmed/29764980 A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation Journal: eLife Published: 18/08/2017 DOI: 10.7554/eLife.23468 URL: https://doi.org/10.7554/eLife.23468 Formative pluripotency: the executive phase in a developmental continuum Journal: Development Published: 01/02/2017 DOI: 10.1242/dev.142679 URL: https://doi.org/10.1242/dev.142679 2016 A conceptual and computational framework for modelling and understanding the non-equilibrium gene regulatory networks of mouse embryonic stem cells. Journal: PLoS Comput Biol Published: 30/11/2016 DOI: 10.1371/journal.pcbi.1005713 URL: https://www.ncbi.nlm.nih.gov/pubmed/28863148 Epigenetic resetting of human pluripotency. Journal: Development Published: 30/11/2016 DOI: 10.1242/dev.146811 URL: https://www.ncbi.nlm.nih.gov/pubmed/28765214 Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters. Journal: Stem Cell Reports Published: 30/11/2016 DOI: 10.1016/j.stemcr.2017.09.005 URL: https://www.ncbi.nlm.nih.gov/pubmed/29020614 NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State. Journal: Stem Cell Reports Published: 30/11/2016 DOI: 10.1016/j.stemcr.2017.05.033 DOI: 10.1101/093880 URL: https://www.ncbi.nlm.nih.gov/pubmed/28669603 The Art of Capturing Pluripotency: Creating the Right Culture. Journal: Stem Cell Reports Published: 30/11/2016 DOI: 10.1016/j.stemcr.2017.05.020 URL: https://www.ncbi.nlm.nih.gov/pubmed/28591647 Tracking the embryonic stem cell transition from ground state pluripotency. Journal: Development Published: 30/11/2016 DOI: 10.1242/dev.142711 URL: https://www.ncbi.nlm.nih.gov/pubmed/28174249 2015 A Method to Identify and Analyze Biological Programs through Automated Reasoning. Journal: NPJ Syst Biol Appl Published: 30/11/2015 DOI: 10.1038/npjsba.2016.10 URL: https://www.ncbi.nlm.nih.gov/pubmed/27668090 Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. Journal: EMBO J Published: 30/11/2015 DOI: 10.15252/embj.201592116 URL: http://www.ncbi.nlm.nih.gov/pubmed/26675138 Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause. Journal: Cell Published: 30/11/2015 DOI: 10.1016/j.cell.2015.12.033 URL: http://www.ncbi.nlm.nih.gov/pubmed/26871632 Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass. Journal: Stem Cell Reports Published: 30/11/2015 DOI: 10.1016/j.stemcr.2016.02.005 URL: http://www.ncbi.nlm.nih.gov/pubmed/26947977 Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency. Journal: EMBO J Published: 30/11/2015 DOI: 10.15252/embj.201592629 URL: http://www.ncbi.nlm.nih.gov/pubmed/26903601 2014 Dynamics of gene silencing during X inactivation using allele-specific RNA-seq. Journal: Genome Biol Published: 30/11/2014 DOI: 10.1186/s13059-015-0698-x URL: http://www.ncbi.nlm.nih.gov/pubmed/26235224 Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis. Journal: Dev Cell Published: 30/11/2014 DOI: 10.1016/j.devcel.2015.10.011 URL: http://www.ncbi.nlm.nih.gov/pubmed/26555056 Looking inwards: opening a window onto human development. Journal: Development Published: 30/11/2014 DOI: 10.1242/dev.119727 URL: https://www.ncbi.nlm.nih.gov/pubmed/25516961 Towards consistent generation of pancreatic lineage progenitors from human pluripotent stem cells. Journal: Philos Trans R Soc Lond B Biol Sci Published: 30/11/2014 DOI: 10.1098/rstb.2014.0365 URL: http://www.ncbi.nlm.nih.gov/pubmed/26416676 2013 A Model-Based Analysis of Culture-Dependent Phenotypes of mESCs. Journal: PLoS One Published: 30/11/2013 DOI: 10.1371/journal.pone.0092496 URL: http://www.ncbi.nlm.nih.gov/pubmed/24643025 Defining an essential transcription factor program for naïve pluripotency. Journal: Science Published: 30/11/2013 DOI: 10.1126/science.1248882 URL: http://www.ncbi.nlm.nih.gov/pubmed/24904165 Genetic exploration of the exit from self-renewal using haploid embryonic stem cells. Journal: Cell Stem Cell Published: 30/11/2013 DOI: 10.1016/j.stem.2013.12.008 URL: http://www.ncbi.nlm.nih.gov/pubmed/24412312 Mapping the route from naive pluripotency to lineage specification. Journal: Philos Trans R Soc Lond B Biol Sci Published: 30/11/2013 DOI: 10.1098/rstb.2013.0540 URL: http://www.ncbi.nlm.nih.gov/pubmed/25349449 Otx2 and Oct4 Drive Early Enhancer Activation during Embryonic Stem Cell Transition from Naive Pluripotency. Journal: Cell Rep Published: 30/11/2013 DOI: 10.1016/j.celrep.2014.05.037 URL: http://www.ncbi.nlm.nih.gov/pubmed/24931607 Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human. Journal: Cell Published: 30/11/2013 DOI: 10.1016/j.cell.2014.08.029 DOI: 10.1016/j.cell.2015.06.052 URL: http://www.ncbi.nlm.nih.gov/pubmed/25215486 The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Journal: Nat Cell Biol Published: 30/11/2013 DOI: 10.1038/ncb2965 URL: http://www.ncbi.nlm.nih.gov/pubmed/24859004 The nature of embryonic stem cells. Journal: Annu Rev Cell Dev Biol Published: 30/11/2013 DOI: 10.1146/annurev-cellbio-100913-013116 URL: http://www.ncbi.nlm.nih.gov/pubmed/25288119 2012 A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1 Journal: PLoS ONE Published: 30/11/2012 DOI: 10.1371/journal.pone.0077053 URL: Automated large-scale culture and medium-throughput chemical screen for modulators of proliferation and viability of human induced pluripotent stem cell-derived neuroepithelial-like stem cells. Journal: J Biomol Screen Published: 30/11/2012 DOI: 10.1177/1087057112461446 URL: https://www.ncbi.nlm.nih.gov/pubmed/23042076 Differentiation of human induced pluripotent stem cells into brown and white adipocytes: Role of Pax3 Journal: STEM CELLS Published: 30/11/2012 DOI: 10.1002/stem.1607 URL: Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Journal: Cell Published: 30/11/2012 DOI: 10.1016/j.cell.2013.03.012 URL: http://www.ncbi.nlm.nih.gov/pubmed/23582324 Identification of the Missing Pluripotency Mediator Downstream of Leukaemia Inhibitory Factor Journal: The EMBO Journal Published: 30/11/2012 DOI: 10.1038/emboj.2013.177 URL: Naive pluripotency is associated with global DNA hypomethylation. Journal: Nat Struct Mol Biol Published: 30/11/2012 DOI: 10.1038/nsmb.2510 URL: http://www.ncbi.nlm.nih.gov/pubmed/23416945 Nanog heterogeneity: tilting at windmills? Journal: Cell Stem Cell Published: 30/11/2012 DOI: 10.1016/j.stem.2013.06.016 URL: http://www.ncbi.nlm.nih.gov/pubmed/23827703 Neural stem cells engrafted in the adult brain fuse with endogenous neurons. Journal: Stem Cells Dev Published: 30/11/2012 DOI: 10.1089/scd.2012.0530 URL: https://www.ncbi.nlm.nih.gov/pubmed/23009360 Rebuilding pluripotency from primordial germ cells Journal: Stem Cell Reports Published: 30/11/2012 URL: Regulation of stem cell therapies under attack in Europe: For whom the bell tolls Journal: EMBO Journal Published: 30/11/2012 URL: Robust self-renewal of rat embryonic stem cells requires fine-tuning of glycogen synthase kinase-3 inhibition Journal: Stem Cell Reports Published: 30/11/2012 URL: Stem cells and regeneration: a special issue. Journal: Development Published: 30/11/2012 DOI: 10.1242/dev.098350 URL: https://www.ncbi.nlm.nih.gov/pubmed/23715535 Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency. Journal: J Neurosci Published: 30/11/2012 DOI: 10.1523/JNEUROSCI.0130-13.2013 URL: http://www.ncbi.nlm.nih.gov/pubmed/23884946 The mammalian germline as a pluripotency cycle. Journal: Development Published: 30/11/2012 DOI: 10.1242/dev.091603 URL: http://www.ncbi.nlm.nih.gov/pubmed/23715543 Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner Journal: Genes and Development Published: 30/11/2012 URL: 2011 A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation. Journal: PLoS Genet Published: 30/11/2011 DOI: 10.1371/journal.pgen.1003112 URL: http://www.ncbi.nlm.nih.gov/pubmed/23271975 A transgenic coagulation factor xiii defective animal and its use for testing wound healing and bleeding Published: 30/11/2011 URL: Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons. Journal: PLoS One Published: 30/11/2011 DOI: 10.1371/journal.pone.0029597 URL: http://www.ncbi.nlm.nih.gov/pubmed/22272239 Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells. Journal: Biol Open Published: 30/11/2011 DOI: 10.1242/bio.2011029 URL: http://www.ncbi.nlm.nih.gov/pubmed/23213369 Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal. Journal: Cell Stem Cell Published: 30/11/2011 DOI: 10.1016/j.stem.2012.06.008 URL: http://www.ncbi.nlm.nih.gov/pubmed/23040478 Germline potential of parthenogenetic haploid mouse embryonic stem cells. Journal: Development Published: 30/11/2011 DOI: 10.1242/dev.083675 URL: http://www.ncbi.nlm.nih.gov/pubmed/22912412 Human hypoblast formation is not dependent on FGF signalling Journal: DEV BIOL Published: 30/11/2011 DOI: 10.1016/j.ydbio.2011.10.030 URL: Imaging, quantification and visualization of spatio-temporal patterning in mESC colonies under different culture conditions Journal: BIOINFORMATICS Published: 30/11/2011 DOI: 10.1093/bioinformatics/bts404 URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000308532300037&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=940c5db9f6a527ba8e12659dac275555 Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid Journal: Neuroscience Research Published: 30/11/2011 URL: JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency. Journal: Nat Commun Published: 30/11/2011 DOI: 10.1038/ncomms1822 URL: http://www.ncbi.nlm.nih.gov/pubmed/22569365 Pluripotency in the embryo and in culture. Journal: Cold Spring Harb Perspect Biol Published: 30/11/2011 DOI: 10.1101/cshperspect.a008128 URL: http://www.ncbi.nlm.nih.gov/pubmed/22855723 Self-organizing circuitry and emergent computation in mouse embryonic stem cells. Journal: Stem Cell Res Published: 30/11/2011 DOI: 10.1016/j.scr.2011.11.001 URL: http://www.ncbi.nlm.nih.gov/pubmed/22169460 The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington’s disease patients demonstrates mutation related enhanced lysosomal activity Journal: NEUROBIOL DIS Published: 30/11/2011 DOI: 10.1016/j.nbd.2011.12.042 URL: The transcriptional and epigenomic foundations of ground state pluripotency. Journal: Cell Published: 30/11/2011 DOI: 10.1016/j.cell.2012.03.026 URL: http://www.ncbi.nlm.nih.gov/pubmed/22541430 Treatment of a Mouse Model of Spinal Cord Injury by Transplantation of Human iPS Cell-derived Long-term Self-renewing Neuroepithelial-like Stem Cells Journal: STEM CELLS Published: 30/11/2011 DOI: 10.1002/stem.1083 URL: http://dx.doi.org/10.1002/stem.1083 2010 Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Journal: NAT CELL BIOL Published: 30/11/2010 DOI: 10.1038/ncb2267 URL: ‘No’ to ban on stem-cell patents Journal: Nature Published: 30/11/2010 DOI: 10.1038/472418a URL: A PiggyBac-based recessive screening method to identify pluripotency regulators. Journal: PLoS One Published: 30/11/2010 DOI: 10.1371/journal.pone.0018189 URL: http://www.ncbi.nlm.nih.gov/pubmed/21533166 Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation Journal: NAT CELL BIOL Published: 30/11/2010 DOI: 10.1038/ncb2267 URL: Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells. Journal: J Cell Sci Published: 30/11/2010 DOI: 10.1242/jcs.085506 URL: http://www.ncbi.nlm.nih.gov/pubmed/21558414 Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions. Journal: Curr Biol Published: 30/11/2010 DOI: 10.1016/j.cub.2010.11.074 URL: http://www.ncbi.nlm.nih.gov/pubmed/21194951 Sox2 and Pax6 Maintain the Proliferative and Developmental Potential of Gliogenic Neural Stem Cells In Vitro Journal: GLIA Published: 30/11/2010 DOI: 10.1002/glia.21201 URL: The liberation of embryonic stem cells. Journal: PLoS Genet Published: 30/11/2010 DOI: 10.1371/journal.pgen.1002019 URL: http://www.ncbi.nlm.nih.gov/pubmed/21490948 The origin and identity of embryonic stem cells Journal: DEVELOPMENT Published: 30/11/2010 DOI: 10.1242/dev.050831 URL: 2009 A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency. Journal: Development Published: 30/11/2009 DOI: 10.1242/dev.052753 URL: http://www.ncbi.nlm.nih.gov/pubmed/20823062 Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state. Journal: Development Published: 30/11/2009 DOI: 10.1242/dev.050427 URL: http://www.ncbi.nlm.nih.gov/pubmed/20519324 Imaging-based chemical screens using normal and glioma-derived neural stem cells. Journal: Biochem Soc Trans Published: 30/11/2009 DOI: 10.1042/BST0381067 URL: http://www.ncbi.nlm.nih.gov/pubmed/20659005 Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Journal: Development Published: 30/11/2009 DOI: 10.1242/dev.046896 URL: http://www.ncbi.nlm.nih.gov/pubmed/20147374 Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. Journal: FASEB J Published: 30/11/2009 DOI: 10.1096/fj.09-139477 URL: http://www.ncbi.nlm.nih.gov/pubmed/19850773 Pluripotent stem cells: private obsession and public expectation. Journal: EMBO Mol Med Published: 30/11/2009 DOI: 10.1002/emmm.201000065 URL: http://www.ncbi.nlm.nih.gov/pubmed/20373283 Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency Journal: CELL STEM CELL Published: 30/11/2009 DOI: 10.1016/j.stem.2010.06.022 URL: The ground state of pluripotency. Journal: Biochem Soc Trans Published: 30/11/2009 DOI: 10.1042/BST0381027 URL: http://www.ncbi.nlm.nih.gov/pubmed/20658998 2008 Brain Cancer Stem Cells: A Level Playing Field Journal: CELL STEM CELL Published: 30/11/2008 DOI: 10.1016/j.stem.2009.10.016 URL: CD133 (Prominin) negative human neural stem cells are clonogenic and tripotent. Journal: PLoS One Published: 30/11/2008 DOI: 10.1371/journal.pone.0005498 URL: http://www.ncbi.nlm.nih.gov/pubmed/19430532 Design principles of pluripotency. Journal: EMBO Mol Med Published: 30/11/2008 DOI: 10.1002/emmm.200900035 URL: http://www.ncbi.nlm.nih.gov/pubmed/20049727 Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Journal: Cell Stem Cell Published: 30/11/2008 DOI: 10.1016/j.stem.2009.03.014 URL: http://www.ncbi.nlm.nih.gov/pubmed/19497285 Induced pluripotent stem cells as a source for multipotent ISL1+cardiovascular progenitors Journal: HUMAN GENE THERAPY Published: 30/11/2008 URL: Klf4 reverts developmentally programmed restriction of ground state pluripotency. Journal: Development Published: 30/11/2008 DOI: 10.1242/dev.030957 URL: http://www.ncbi.nlm.nih.gov/pubmed/19224983 Naive and primed pluripotent states. Journal: Cell Stem Cell Published: 30/11/2008 DOI: 10.1016/j.stem.2009.05.015 URL: http://www.ncbi.nlm.nih.gov/pubmed/19497275 Nanog is the gateway to the pluripotent ground state. Journal: Cell Published: 30/11/2008 DOI: 10.1016/j.cell.2009.07.039 URL: http://www.ncbi.nlm.nih.gov/pubmed/19703398 Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal. Journal: Cell Stem Cell Published: 30/11/2008 DOI: 10.1016/j.stem.2009.11.003 URL: http://www.ncbi.nlm.nih.gov/pubmed/19951688 Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Journal: Development Published: 30/11/2008 DOI: 10.1242/dev.038893 URL: http://www.ncbi.nlm.nih.gov/pubmed/19710168 Validated germline-competent embryonic stem cell lines from nonobese diabetic mice. Journal: Nat Med Published: 30/11/2008 DOI: 10.1038/nm.1996 URL: http://www.ncbi.nlm.nih.gov/pubmed/19491843 2007 Capture of authentic embryonic stem cells from rat blastocysts. Journal: Cell Published: 30/11/2007 DOI: 10.1016/j.cell.2008.12.007 URL: http://www.ncbi.nlm.nih.gov/pubmed/19109897 Capturing pluripotency. Journal: Cell Published: 30/11/2007 DOI: 10.1016/j.cell.2008.02.006 URL: http://www.ncbi.nlm.nih.gov/pubmed/18295569 Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation. Journal: Mol Cell Neurosci Published: 30/11/2007 DOI: 10.1016/j.mcn.2008.03.012 URL: http://www.ncbi.nlm.nih.gov/pubmed/18504136 Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture. Journal: Mol Cell Neurosci Published: 30/11/2007 DOI: 10.1016/j.mcn.2008.02.014 URL: http://www.ncbi.nlm.nih.gov/pubmed/18450476 Parameters influencing derivation of embryonic stem cells from murine embryos. Journal: Genesis Published: 30/11/2007 DOI: 10.1002/dvg.20442 URL: http://www.ncbi.nlm.nih.gov/pubmed/18837461 Promotion of reprogramming to ground state pluripotency by signal inhibition. Journal: PLoS biology Published: 30/11/2007 URL: The ground state of embryonic stem cell self-renewal Journal: NATURE Published: 30/11/2007 DOI: 10.1038/nature06968 URL: 2006 Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells Journal: Stem Cells Published: 30/11/2006 DOI: 10.1634/stemcells.2006-0445 URL: FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment Journal: DEVELOPMENT Published: 30/11/2006 DOI: 10.1242/dev.02880 URL: Nanog safeguards pluripotency and mediates germline development. Journal: Nature Published: 30/11/2006 DOI: 10.1038/nature06403 URL: http://www.ncbi.nlm.nih.gov/pubmed/18097409 Neuroepithelial cells supply an initial transient wave of MSC differentiation. Journal: Cell Published: 30/11/2006 DOI: 10.1016/j.cell.2007.04.028 URL: http://www.ncbi.nlm.nih.gov/pubmed/17604725 Tripotential Differentiation of Adherently Expandable Neural Stem (NS) Cells Journal: PLOS ONE Published: 30/11/2006 DOI: 10.1371/journal.pone.0000298 URL: 2005 A glossary for stem-cell biology Journal: NATURE Published: 30/11/2005 DOI: 10.1038/Nature04954 URL: Adherent neural stem (NS) cells from fetal and adult forebrain Journal: Cerebral Cortex Published: 30/11/2005 DOI: 10.1093/cercor/bbhj167 URL: Embryonic stem cells: potency and potential Journal: EMBO Science & Society paper, Stem Cell Research - Status Prospectus Prerequisites Published: 30/11/2005 URL: Exploitation of adherent neural stem cells in basic and applied neurobiology Journal: REGENERATIVE MEDICINE Published: 30/11/2005 DOI: 10.2217/17460751.1.1.111 URL: Nanog promotes transfer of pluripotency after cell fusion. Journal: Nature Published: 30/11/2005 DOI: 10.1038/nature04914 URL: http://www.ncbi.nlm.nih.gov/pubmed/16791199 Notch promotes neural lineage entry by pluripotent embryonic stem cells Journal: PLOS BIOL Published: 30/11/2005 DOI: 10.1371/journal.pbio.0040121 URL: Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus Journal: Stem Cells Published: 30/11/2005 DOI: 10.1634/stemcells.2006-0050 URL: 2004 Characterization of the uterine phenotype during the peri-implantation period for LIF-null, MF1 strain mice Journal: DEVELOPMENTAL BIOLOGY Published: 30/11/2004 DOI: 10.1016/j.ydbio.2005.01.033 URL: Human embryonic stem cells Journal: SCIENCE Published: 30/11/2004 URL: Niche-independent symmetrical self-renewal of a mammalian tissue stem cell Journal: Plos Biology Published: 30/11/2004 DOI: 10.1371/journal.pbio.0030283 URL: Osteogenic and chondrogenic differentiation of embryonic stem cells in response to specific growth factors Journal: Bone Published: 30/11/2004 DOI: 10.1016/j.bone.2004.07.019 URL: The battlefield of pluripotency Journal: CELL Published: 30/11/2004 DOI: 10.1016/j.cell.2005.11.012 URL: Understanding embryonic stem cells Journal: Placenta Published: 30/11/2004 URL: Unequal segregation of parental chromosomes in embryonic stem cell hybrids Journal: Molecular Reproduction and Development Published: 30/11/2004 DOI: 10.1002/Mrd.20266 URL: 2003 Control of ES cell self renewal and lineage specification, and medium therefore including rat ES cells Published: 30/11/2003 URL: Control of ES cell self renewal and lineage specification, and medium therefor Published: 30/11/2003 URL: Converting ES cells into neurons Journal: Stem Cells in the Nervous System: Functional and Clinical Implications Published: 30/11/2003 DOI: 10.1007/978-3-642-18883-1 ISBN: 978-3-642-18883-1 URL: ES cells: Research progress in UK Journal: Cell Technology (Japan) Published: 30/11/2003 URL: Identification of genes regulated by leukemia-inhibitory factor in the mouse uterus at the time of implantation. Journal: Mol Endocrinol Published: 30/11/2003 DOI: 10.1210/me.2004-0110 URL: http://www.ncbi.nlm.nih.gov/pubmed/15178747 Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar Journal: Developmental Dynamics Published: 30/11/2003 DOI: 10.1002/Dvdy.20003 URL: Regulation of neural stem cells by beta amyloid in vitro Journal: Neurobiology of Aging Published: 30/11/2003 URL: Regulation of uterine gene expression by leukaemia inhibitory factor Journal: Biology of Reproduction Published: 30/11/2003 URL: Self-renewal of teratocarcinoma and embryonic stem cells Journal: Oncogene Published: 30/11/2003 DOI: 10.1038/sj.onc.1207930 URL: SoxB transcription factors specify neuroectodermal lineage choice in ES cells Journal: MOLECULAR AND CELLULAR NEUROSCIENCE Published: 30/11/2003 DOI: 10.1016/j.mcn.2004.08.002 URL: The differentiation of ES cells into neuroectodermal precursors is associated with an increase in the levels and sulfation of heparan sulfate proteoglycans Journal: INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Published: 30/11/2003 URL: 2002 An unpaired mouse centromere passes consistently through male meiosis and does not significantly compromise spermatogenesis Journal: Chromosoma Published: 30/11/2002 DOI: 10.1007/s00412-003-0260-6 URL: BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3 Journal: CELL Published: 30/11/2002 URL: Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture Journal: NATURE BIOTECHNOLOGY Published: 30/11/2002 DOI: 10.1038/Nbt780 URL: Defined conditions for neural commitment and differentiation Journal: Methods in Enzymology Published: 30/11/2002 URL: Differentiation and gene regulation programming, reprogramming and regeneration – Editorial overview Journal: CURRENT OPINION IN GENETICS & DEVELOPMENT Published: 30/11/2002 DOI: 10.1016/j.gde.2003.08.013 URL: Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles Journal: NATURE BIOTECHNOLOGY Published: 30/11/2002 DOI: 10.1038/Nbt804 URL: Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells Journal: CELL Published: 30/11/2002 URL: Genesis of embryonic stem cells Journal: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES Published: 30/11/2002 DOI: 10.1098/rstb.2003.1327 URL: Lineage allocation and asymmetries in the early mouse embryo – Discussion Journal: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES Published: 30/11/2002 URL: Neural differentiation of mouse embryonic stem cells Journal: BIOCHEMICAL SOCIETY TRANSACTIONS Published: 30/11/2002 URL: Rapid loss of Oct-4 and pluripotency in cultured rodent blastocysts and derivative cell lines Journal: Biology of Reproduction Published: 30/11/2002 DOI: 10.1095/biolreprod.102.006197 URL: Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Published: 30/11/2002 DOI: 10.1073/pnas.1734197100 URL: Specification of germ cell fate in mice. Journal: Philos Trans R Soc Lond B Biol Sci Published: 30/11/2002 DOI: 10.1098/rstb.2003.1324 URL: https://www.ncbi.nlm.nih.gov/pubmed/14511483 Stem cells – Fusion brings down barriers Journal: NATURE Published: 30/11/2002 DOI: 10.1038/422823a URL: The role of Oct-4 in early post-implantation development Journal: Genetical Research Published: 30/11/2002 URL: 2001 Changing potency by spontaneous fusion Journal: NATURE Published: 30/11/2001 URL: Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation Journal: NATURE BIOTECHNOLOGY Published: 30/11/2001 DOI: 10.1038/Nbt763 URL: Human embryonic stem cells: prospects for human health – a 1-day international symposium held at the University of Sheffield Journal: Journal of Anatomy Published: 30/11/2001 URL: Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells Journal: Journal of Cell Science Published: 30/11/2001 DOI: 10.1242/Jcs.00049 URL: Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells Journal: MOLECULAR AND CELLULAR BIOLOGY Published: 30/11/2001 URL: Signalling, cell cycle and pluripotency in embryonic stem cells Journal: Trends in Cell Biology Published: 30/11/2001 URL: Targeted inactivation of the mouse locus encoding coagulation factor XIII-A: Hemostatic abnormalities in mutant mice and characterization of the coagulation deficit Journal: THROMBOSIS AND HAEMOSTASIS Published: 30/11/2001 URL: 2000 Embryo-derived stem cells: Of mice and men Journal: Annual Review of Cell and Developmental Biology Published: 30/11/2000 URL: Embryonic Stem Cells Journal: Stem cell biology Published: 30/11/2000 ISBN: 978-0879695750 URL: Lineage selection and isolation of neural precursor from embryonic stem cells Journal: Brain Stem Cells Published: 30/11/2000 URL: Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines Journal: DEVELOPMENT Published: 30/11/2000 URL: Self-renewal and differentiation of pluripotent embryonic stem cells. Journal: DEVELOPMENTAL BIOLOGY Published: 30/11/2000 URL: 1999 A structurally defined mini-chromosome vector for the mouse germ line Journal: Current Biology Published: 30/11/1999 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10660300 Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice Journal: Neuron Published: 30/11/1999 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10839370 Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells Journal: Nature Genetics Published: 30/11/1999 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10742100 1998 Adaptive responses to environmental chemicals. Journal: Biochem Soc Symp Published: 30/11/1998 URL: https://www.ncbi.nlm.nih.gov/pubmed/10207626 Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice Journal: Science Published: 30/11/1998 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10558995 Leukemia inhibitory factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade Journal: Journal of Biological Chemistry Published: 30/11/1998 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10455174 New prospects for human stem-cell therapy in the nervous system. Journal: Trends Neurosci Published: 30/11/1998 URL: http://www.ncbi.nlm.nih.gov/pubmed/10407421 Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells Journal: Cells, Tissues, Organs Published: 30/11/1998 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10592385 Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses Journal: European Journal of Immunology Published: 30/11/1998 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10229092 Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells Journal: Developmental Biology Published: 30/11/1998 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10364425 1997 Cell Therapy: In search of pluripotency Journal: Current Biology Published: 30/11/1997 URL: Differential stability of a human mini-chromosome in mouse cell lines Journal: Chromosoma Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9745051 Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4 Journal: Cell Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9814708 Generation of purified neural precursors from embryonic stem cells by lineage selection Journal: Current Biology Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9742400 Histochemical and ultrastructural modification of mucosal mast cell granules in parasitized mice lacking the beta-chymase, mouse mast cell protease-1 Journal: The American Journal of Pathology Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9708809 Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases Journal: Proceedings of the National Academy of Sciences of USA Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9560266 Maintenance of pluripotential embryonic stem cells by stem cell selection Journal: Reproduction Fertility and Development Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10612458 Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway Journal: Developmental Biology Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9806780 Rat and mouse epiblasts differ in their capacity to generate extraembryonic endoderm Journal: Reproduction Fertility and Development Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10612457 Rat and mouse epiblasts differ in their capacity to generate extraembryonic endoderm. Journal: Reprod Fertil Dev Published: 30/11/1997 URL: https://www.ncbi.nlm.nih.gov/pubmed/10612457 Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 Journal: Genes and Development Published: 30/11/1997 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9649508 The use of transgenic animals to assess the role of metabolism in target organ toxicity Journal: Archives of toxicology. Supplement. Published: 30/11/1997 URL: 1996 A Schwann cell mitogen accompanying regeneration of motor neurons. Journal: Nature Published: 30/11/1996 DOI: 10.1038/37615 URL: http://www.ncbi.nlm.nih.gov/pubmed/9403691 Differentiation of embryonic stem cells into adipocytes in vitro Journal: Cell Science Published: 30/11/1996 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9202388 HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice Journal: Journal of Experimental Medicine Published: 30/11/1996 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9182675 Human mini-chromosomes in mouse embryonal stem cells Journal: Human Molecular Genetics Published: 30/11/1996 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9259287 Improved EBV-based shuttle vector system: dicistronic mRNA couples the synthesis of the Epstein-Barr nuclear antigen-1 protein to neomycin resistance Journal: Genes and Development Published: 30/11/1996 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9332352 Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos Journal: Proceedings of the National Academy of Sciences of USA Published: 30/11/1996 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9275227 Muller-cell-derived leukaemia inhibitory factor arrests rod photoreceptor differentiation at a postmitotic pre-rod stage of development Journal: Development Published: 30/11/1996 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9199361 Structure of the mouse leukaemia inhibitory factor receptor gene: regulated expression of mRNA encoding a soluble receptor isoform from an alternative 5′ untranslated region Journal: Biochemical Journal Published: 30/11/1996 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9396734 1995 Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis Journal: Mechanisms of Development Published: 30/11/1995 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8843390 Identification of a developmentally regulated protein tyrosine phosphatase in embryonic stem cells that is a marker of pluripotential epiblast and early mesoderm Journal: Mechanisms of Development Published: 30/11/1995 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8951793 1994 Altered immune responses in mice lacking inducible nitric oxide synthase Journal: Nature Published: 30/11/1994 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7539113 Essential function of LIF receptor in motor neurons Journal: Nature Published: 30/11/1994 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7501019 Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis Journal: Trends in Genetics Published: 30/11/1994 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7540337 1993 Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor Journal: Experimental Cell Research Published: 30/11/1993 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7957676 Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression Journal: Proceedings of the National Academy of Sciences Published: 30/11/1993 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8183905 Embryonic Stem Cells and Haematopoiesis Journal: Culture of hematopoietic cells Published: 30/11/1993 ISBN: 9780471588306 URL: Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways Journal: Mechanisms of Development Published: 30/11/1993 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8199053 1992 Expression of alternative forms of differentiation inhibiting activity (DIA/LIF) during murine embryogenesis and in neonatal and adult tissues Journal: Developmental Genetics Published: 30/11/1992 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7689430 Telomere directed fragmentation of mammalian chromosomes Journal: Nuclei Acids Research Published: 30/11/1992 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8441617 The responsiveness of embryonic stem cells to alpha and beta interferons provides the basis of an inducible expression system for analysis of developmental control genes Journal: Molecular and Cellular Biology Published: 30/11/1992 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8247011 1991 A rapid and efficient method for freezing and recovering clones of embryonic stem cells Journal: Trends in Genetics Published: 30/11/1991 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1369735 Differentiation inhibiting activity (DIA/LIF) and mouse development Journal: Developmental Biology Published: 30/11/1991 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1601171 Introduction: Mammalian Stem Cell Systems Journal: Seminars in Cell Biology Published: 30/11/1991 DOI: 10.1016/1043-4682(92)90009-K URL: Mouse embryo stem cells: their identification, propagation and manipulation Journal: Seminars in Cell Biology Published: 30/11/1991 URL: 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Journal: Seminars in Cell Biology Published: 30/11/1990 URL: 1989 Developmentally programmed induction of differentiation inhibiting activity and the control of stem cell populations Journal: Genes and Development Published: 30/11/1989 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1703981 Differentiation inhibiting activity is produced in matrix-associated and diffusible forms that are generated by alternate promoter usage Journal: Cell Published: 30/11/1989 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2119255 Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity Journal: Development (Cambridge) Published: 30/11/1989 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2129226 Growth and Differentiation factors in embryonic stem cell function Journal: Journal of Cell Science Suplement Published: 30/11/1989 URL: Leukemia inhibitory factor LIF/Differentiation-Inhibiting activity (DIA)/human interleukin for DA cells (HILDA) augments proliferation of human hematopoietic cells. Journal: Blood Published: 30/11/1989 URL: 1988 Growth and differentiation factors of embryonic stem cells Journal: Cell to cell signalling in mammalian Development Published: 30/11/1988 URL: Growth factors in embryogenesis Journal: British Medical Bulletin Published: 30/11/1988 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2688809 1987 Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides Journal: Nature Published: 30/11/1987 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3143917 Regulatory factors of embryonic stem cells Journal: J Cell Sci Suppl Published: 30/11/1987 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3077939 1986 Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells Journal: Developmental Biology Published: 30/11/1986 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3569655 1985 Selection of a mouse embryonal carcinoma clone resistant to the inhibition of metabolic cooperation by retinoic acid Journal: Experimental Cell Research Published: 30/11/1985 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3720856