Prof Austin Smith

Director of Living Systems Institute

Austin.Smith@exeter.ac.uk

CLES

Groups: Smith Group

University profile

0000-0002-3029-4682

Publications

2020

Disabling de novo DNA methylation in embryonic stem cells allows an illegitimate fate trajectory

Published: 20/12/2020
DOI: 10.1101/2020.12.20.423404
URL: https://doi.org/10.1101/2020.12.20.423404

Cancer-Related Mutations Are Not Enriched in Naive Human Pluripotent Stem Cells

Journal: Cell Stem Cell

Published: 30/11/2020
ISSN: 1934-5909
DOI: https://doi.org/10.1016/j.stem.2020.11.014
URL: http://www.sciencedirect.com/science/article/pii/S193459092030552X

Embryonic stem cells commit to differentiation by symmetric divisions following a variable lag period

Published: 18/06/2020
DOI: 10.1101/2020.06.17.157578
URL: https://doi.org/10.1101/2020.06.17.157578

Trophectoderm Potency is Retained Exclusively in Human Naïve Cells

Published: 04/02/2020
DOI: 10.1101/2020.02.04.933812
URL: https://doi.org/10.1101/2020.02.04.933812

Zfp281 orchestrates interconversion of pluripotent states by engaging Ehmt1 and Zic2

Journal: The EMBO Journal

Published: 15/01/2020
DOI: 10.15252/embj.2019102591
URL: https://doi.org/10.15252/embj.2019102591

2019

Microfluidic platform for 3D cell culture with live imaging and clone retrieval

Journal: Lab on a Chip

Published: 30/11/2019
DOI: 10.1039/D0LC00165A
URL: https://doi.org/10.1039/D0LC00165A

Capacitation of human naïve pluripotent stem cells for multi-lineage differentiation

Journal: Development

Published: 01/04/2019
DOI: 10.1242/dev.172916
URL: https://doi.org/10.1242/dev.172916

Defined conditions for propagation and manipulation of mouse embryonic stem cells

Journal: Development

Published: 15/03/2019
DOI: 10.1242/dev.173146
URL: https://doi.org/10.1242/dev.173146

2018

A common molecular logic determines embryonic stem cell self‐renewal and reprogramming

Journal: The EMBO Journal

Published: 31/12/2018
DOI: 10.15252/embj.2018100003
URL: https://doi.org/10.15252/embj.2018100003

Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development

Journal: Development

Published: 01/11/2018
DOI: 10.1242/dev.167833
URL: https://doi.org/10.1242/dev.167833

Negative feedback via RSK modulates Erk‐dependent progression from naïve pluripotency

Journal: EMBO reports

Published: 31/07/2018
DOI: 10.15252/embr.201745642
URL: https://doi.org/10.15252/embr.201745642

Pluripotency Deconstructed

Journal: Development, Growth & Differentiation

Published: 23/01/2018
DOI: 10.1111/dgd.12419
URL: https://doi.org/10.1111/dgd.12419

Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblast

Journal: Development

Published: 01/01/2018
DOI: 10.1242/dev.158501
URL: https://doi.org/10.1242/dev.158501

2017

Esrrb Complementation Rescues Development of Nanog-Null Germ Cells.

Journal: Cell Rep

Published: 30/11/2017
DOI: 10.1016/j.celrep.2017.12.060
URL: https://www.ncbi.nlm.nih.gov/pubmed/29320730

Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.

Journal: EMBO J

Published: 30/11/2017
DOI: 10.15252/embj.201798133
URL: https://www.ncbi.nlm.nih.gov/pubmed/29764980

A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation

Journal: eLife

Published: 18/08/2017
DOI: 10.7554/eLife.23468
URL: https://doi.org/10.7554/eLife.23468

Formative pluripotency: the executive phase in a developmental continuum

Journal: Development

Published: 01/02/2017
DOI: 10.1242/dev.142679
URL: https://doi.org/10.1242/dev.142679

2016

A conceptual and computational framework for modelling and understanding the non-equilibrium gene regulatory networks of mouse embryonic stem cells.

Journal: PLoS Comput Biol

Published: 30/11/2016
DOI: 10.1371/journal.pcbi.1005713
URL: https://www.ncbi.nlm.nih.gov/pubmed/28863148

Epigenetic resetting of human pluripotency.

Journal: Development

Published: 30/11/2016
DOI: 10.1242/dev.146811
URL: https://www.ncbi.nlm.nih.gov/pubmed/28765214

Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters.

Journal: Stem Cell Reports

Published: 30/11/2016
DOI: 10.1016/j.stemcr.2017.09.005
URL: https://www.ncbi.nlm.nih.gov/pubmed/29020614

NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State.

Journal: Stem Cell Reports

Published: 30/11/2016
DOI: 10.1016/j.stemcr.2017.05.033
DOI: 10.1101/093880
URL: https://www.ncbi.nlm.nih.gov/pubmed/28669603

The Art of Capturing Pluripotency: Creating the Right Culture.

Journal: Stem Cell Reports

Published: 30/11/2016
DOI: 10.1016/j.stemcr.2017.05.020
URL: https://www.ncbi.nlm.nih.gov/pubmed/28591647

Tracking the embryonic stem cell transition from ground state pluripotency.

Journal: Development

Published: 30/11/2016
DOI: 10.1242/dev.142711
URL: https://www.ncbi.nlm.nih.gov/pubmed/28174249

2015

A Method to Identify and Analyze Biological Programs through Automated Reasoning.

Journal: NPJ Syst Biol Appl

Published: 30/11/2015
DOI: 10.1038/npjsba.2016.10
URL: https://www.ncbi.nlm.nih.gov/pubmed/27668090

Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification.

Journal: EMBO J

Published: 30/11/2015
DOI: 10.15252/embj.201592116
URL: http://www.ncbi.nlm.nih.gov/pubmed/26675138

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause.

Journal: Cell

Published: 30/11/2015
DOI: 10.1016/j.cell.2015.12.033
URL: http://www.ncbi.nlm.nih.gov/pubmed/26871632

Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass.

Journal: Stem Cell Reports

Published: 30/11/2015
DOI: 10.1016/j.stemcr.2016.02.005
URL: http://www.ncbi.nlm.nih.gov/pubmed/26947977

Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency.

Journal: EMBO J

Published: 30/11/2015
DOI: 10.15252/embj.201592629
URL: http://www.ncbi.nlm.nih.gov/pubmed/26903601

2014

Dynamics of gene silencing during X inactivation using allele-specific RNA-seq.

Journal: Genome Biol

Published: 30/11/2014
DOI: 10.1186/s13059-015-0698-x
URL: http://www.ncbi.nlm.nih.gov/pubmed/26235224

Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis.

Journal: Dev Cell

Published: 30/11/2014
DOI: 10.1016/j.devcel.2015.10.011
URL: http://www.ncbi.nlm.nih.gov/pubmed/26555056

Looking inwards: opening a window onto human development.

Journal: Development

Published: 30/11/2014
DOI: 10.1242/dev.119727
URL: https://www.ncbi.nlm.nih.gov/pubmed/25516961

Towards consistent generation of pancreatic lineage progenitors from human pluripotent stem cells.

Journal: Philos Trans R Soc Lond B Biol Sci

Published: 30/11/2014
DOI: 10.1098/rstb.2014.0365
URL: http://www.ncbi.nlm.nih.gov/pubmed/26416676

2013

A Model-Based Analysis of Culture-Dependent Phenotypes of mESCs.

Journal: PLoS One

Published: 30/11/2013
DOI: 10.1371/journal.pone.0092496
URL: http://www.ncbi.nlm.nih.gov/pubmed/24643025

Defining an essential transcription factor program for naïve pluripotency.

Journal: Science

Published: 30/11/2013
DOI: 10.1126/science.1248882
URL: http://www.ncbi.nlm.nih.gov/pubmed/24904165

Genetic exploration of the exit from self-renewal using haploid embryonic stem cells.

Journal: Cell Stem Cell

Published: 30/11/2013
DOI: 10.1016/j.stem.2013.12.008
URL: http://www.ncbi.nlm.nih.gov/pubmed/24412312

Mapping the route from naive pluripotency to lineage specification.

Journal: Philos Trans R Soc Lond B Biol Sci

Published: 30/11/2013
DOI: 10.1098/rstb.2013.0540
URL: http://www.ncbi.nlm.nih.gov/pubmed/25349449

Otx2 and Oct4 Drive Early Enhancer Activation during Embryonic Stem Cell Transition from Naive Pluripotency.

Journal: Cell Rep

Published: 30/11/2013
DOI: 10.1016/j.celrep.2014.05.037
URL: http://www.ncbi.nlm.nih.gov/pubmed/24931607

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human.

Journal: Cell

Published: 30/11/2013
DOI: 10.1016/j.cell.2014.08.029
DOI: 10.1016/j.cell.2015.06.052
URL: http://www.ncbi.nlm.nih.gov/pubmed/25215486

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.

Journal: Nat Cell Biol

Published: 30/11/2013
DOI: 10.1038/ncb2965
URL: http://www.ncbi.nlm.nih.gov/pubmed/24859004

The nature of embryonic stem cells.

Journal: Annu Rev Cell Dev Biol

Published: 30/11/2013
DOI: 10.1146/annurev-cellbio-100913-013116
URL: http://www.ncbi.nlm.nih.gov/pubmed/25288119

2012

A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1

Journal: PLoS ONE

Published: 30/11/2012
DOI: 10.1371/journal.pone.0077053
URL:

Automated large-scale culture and medium-throughput chemical screen for modulators of proliferation and viability of human induced pluripotent stem cell-derived neuroepithelial-like stem cells.

Journal: J Biomol Screen

Published: 30/11/2012
DOI: 10.1177/1087057112461446
URL: https://www.ncbi.nlm.nih.gov/pubmed/23042076

Differentiation of human induced pluripotent stem cells into brown and white adipocytes: Role of Pax3

Journal: STEM CELLS

Published: 30/11/2012
DOI: 10.1002/stem.1607
URL:

Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.

Journal: Cell

Published: 30/11/2012
DOI: 10.1016/j.cell.2013.03.012
URL: http://www.ncbi.nlm.nih.gov/pubmed/23582324

Identification of the Missing Pluripotency Mediator Downstream of Leukaemia Inhibitory Factor

Journal: The EMBO Journal

Published: 30/11/2012
DOI: 10.1038/emboj.2013.177
URL:

Naive pluripotency is associated with global DNA hypomethylation.

Journal: Nat Struct Mol Biol

Published: 30/11/2012
DOI: 10.1038/nsmb.2510
URL: http://www.ncbi.nlm.nih.gov/pubmed/23416945

Nanog heterogeneity: tilting at windmills?

Journal: Cell Stem Cell

Published: 30/11/2012
DOI: 10.1016/j.stem.2013.06.016
URL: http://www.ncbi.nlm.nih.gov/pubmed/23827703

Neural stem cells engrafted in the adult brain fuse with endogenous neurons.

Journal: Stem Cells Dev

Published: 30/11/2012
DOI: 10.1089/scd.2012.0530
URL: https://www.ncbi.nlm.nih.gov/pubmed/23009360

Rebuilding pluripotency from primordial germ cells

Journal: Stem Cell Reports

Published: 30/11/2012
URL:

Regulation of stem cell therapies under attack in Europe: For whom the bell tolls

Journal: EMBO Journal

Published: 30/11/2012
URL:

Robust self-renewal of rat embryonic stem cells requires fine-tuning of glycogen synthase kinase-3 inhibition

Journal: Stem Cell Reports

Published: 30/11/2012
URL:

Stem cells and regeneration: a special issue.

Journal: Development

Published: 30/11/2012
DOI: 10.1242/dev.098350
URL: https://www.ncbi.nlm.nih.gov/pubmed/23715535

Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency.

Journal: J Neurosci

Published: 30/11/2012
DOI: 10.1523/JNEUROSCI.0130-13.2013
URL: http://www.ncbi.nlm.nih.gov/pubmed/23884946

The mammalian germline as a pluripotency cycle.

Journal: Development

Published: 30/11/2012
DOI: 10.1242/dev.091603
URL: http://www.ncbi.nlm.nih.gov/pubmed/23715543

Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner

Journal: Genes and Development

Published: 30/11/2012
URL:

2011

A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation.

Journal: PLoS Genet

Published: 30/11/2011
DOI: 10.1371/journal.pgen.1003112
URL: http://www.ncbi.nlm.nih.gov/pubmed/23271975

A transgenic coagulation factor xiii defective animal and its use for testing wound healing and bleeding

Published: 30/11/2011
URL:

Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons.

Journal: PLoS One

Published: 30/11/2011
DOI: 10.1371/journal.pone.0029597
URL: http://www.ncbi.nlm.nih.gov/pubmed/22272239

Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells.

Journal: Biol Open

Published: 30/11/2011
DOI: 10.1242/bio.2011029
URL: http://www.ncbi.nlm.nih.gov/pubmed/23213369

Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal.

Journal: Cell Stem Cell

Published: 30/11/2011
DOI: 10.1016/j.stem.2012.06.008
URL: http://www.ncbi.nlm.nih.gov/pubmed/23040478

Germline potential of parthenogenetic haploid mouse embryonic stem cells.

Journal: Development

Published: 30/11/2011
DOI: 10.1242/dev.083675
URL: http://www.ncbi.nlm.nih.gov/pubmed/22912412

Human hypoblast formation is not dependent on FGF signalling

Journal: DEV BIOL

Published: 30/11/2011
DOI: 10.1016/j.ydbio.2011.10.030
URL:

Imaging, quantification and visualization of spatio-temporal patterning in mESC colonies under different culture conditions

Journal: BIOINFORMATICS

Published: 30/11/2011
DOI: 10.1093/bioinformatics/bts404
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000308532300037&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=940c5db9f6a527ba8e12659dac275555

Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid

Journal: Neuroscience Research

Published: 30/11/2011
URL:

JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency.

Journal: Nat Commun

Published: 30/11/2011
DOI: 10.1038/ncomms1822
URL: http://www.ncbi.nlm.nih.gov/pubmed/22569365

Pluripotency in the embryo and in culture.

Journal: Cold Spring Harb Perspect Biol

Published: 30/11/2011
DOI: 10.1101/cshperspect.a008128
URL: http://www.ncbi.nlm.nih.gov/pubmed/22855723

Self-organizing circuitry and emergent computation in mouse embryonic stem cells.

Journal: Stem Cell Res

Published: 30/11/2011
DOI: 10.1016/j.scr.2011.11.001
URL: http://www.ncbi.nlm.nih.gov/pubmed/22169460

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington’s disease patients demonstrates mutation related enhanced lysosomal activity

Journal: NEUROBIOL DIS

Published: 30/11/2011
DOI: 10.1016/j.nbd.2011.12.042
URL:

The transcriptional and epigenomic foundations of ground state pluripotency.

Journal: Cell

Published: 30/11/2011
DOI: 10.1016/j.cell.2012.03.026
URL: http://www.ncbi.nlm.nih.gov/pubmed/22541430

Treatment of a Mouse Model of Spinal Cord Injury by Transplantation of Human iPS Cell-derived Long-term Self-renewing Neuroepithelial-like Stem Cells

Journal: STEM CELLS

Published: 30/11/2011
DOI: 10.1002/stem.1083
URL: http://dx.doi.org/10.1002/stem.1083

2010

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.

Journal: NAT CELL BIOL

Published: 30/11/2010
DOI: 10.1038/ncb2267
URL:

‘No’ to ban on stem-cell patents

Journal: Nature

Published: 30/11/2010
DOI: 10.1038/472418a
URL:

A PiggyBac-based recessive screening method to identify pluripotency regulators.

Journal: PLoS One

Published: 30/11/2010
DOI: 10.1371/journal.pone.0018189
URL: http://www.ncbi.nlm.nih.gov/pubmed/21533166

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

Journal: NAT CELL BIOL

Published: 30/11/2010
DOI: 10.1038/ncb2267
URL:

Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells.

Journal: J Cell Sci

Published: 30/11/2010
DOI: 10.1242/jcs.085506
URL: http://www.ncbi.nlm.nih.gov/pubmed/21558414

Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions.

Journal: Curr Biol

Published: 30/11/2010
DOI: 10.1016/j.cub.2010.11.074
URL: http://www.ncbi.nlm.nih.gov/pubmed/21194951

Sox2 and Pax6 Maintain the Proliferative and Developmental Potential of Gliogenic Neural Stem Cells In Vitro

Journal: GLIA

Published: 30/11/2010
DOI: 10.1002/glia.21201
URL:

The liberation of embryonic stem cells.

Journal: PLoS Genet

Published: 30/11/2010
DOI: 10.1371/journal.pgen.1002019
URL: http://www.ncbi.nlm.nih.gov/pubmed/21490948

The origin and identity of embryonic stem cells

Journal: DEVELOPMENT

Published: 30/11/2010
DOI: 10.1242/dev.050831
URL:

2009

A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency.

Journal: Development

Published: 30/11/2009
DOI: 10.1242/dev.052753
URL: http://www.ncbi.nlm.nih.gov/pubmed/20823062

Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state.

Journal: Development

Published: 30/11/2009
DOI: 10.1242/dev.050427
URL: http://www.ncbi.nlm.nih.gov/pubmed/20519324

Imaging-based chemical screens using normal and glioma-derived neural stem cells.

Journal: Biochem Soc Trans

Published: 30/11/2009
DOI: 10.1042/BST0381067
URL: http://www.ncbi.nlm.nih.gov/pubmed/20659005

Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos.

Journal: Development

Published: 30/11/2009
DOI: 10.1242/dev.046896
URL: http://www.ncbi.nlm.nih.gov/pubmed/20147374

Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors.

Journal: FASEB J

Published: 30/11/2009
DOI: 10.1096/fj.09-139477
URL: http://www.ncbi.nlm.nih.gov/pubmed/19850773

Pluripotent stem cells: private obsession and public expectation.

Journal: EMBO Mol Med

Published: 30/11/2009
DOI: 10.1002/emmm.201000065
URL: http://www.ncbi.nlm.nih.gov/pubmed/20373283

Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency

Journal: CELL STEM CELL

Published: 30/11/2009
DOI: 10.1016/j.stem.2010.06.022
URL:

The ground state of pluripotency.

Journal: Biochem Soc Trans

Published: 30/11/2009
DOI: 10.1042/BST0381027
URL: http://www.ncbi.nlm.nih.gov/pubmed/20658998

2008

Brain Cancer Stem Cells: A Level Playing Field

Journal: CELL STEM CELL

Published: 30/11/2008
DOI: 10.1016/j.stem.2009.10.016
URL:

CD133 (Prominin) negative human neural stem cells are clonogenic and tripotent.

Journal: PLoS One

Published: 30/11/2008
DOI: 10.1371/journal.pone.0005498
URL: http://www.ncbi.nlm.nih.gov/pubmed/19430532

Design principles of pluripotency.

Journal: EMBO Mol Med

Published: 30/11/2008
DOI: 10.1002/emmm.200900035
URL: http://www.ncbi.nlm.nih.gov/pubmed/20049727

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.

Journal: Cell Stem Cell

Published: 30/11/2008
DOI: 10.1016/j.stem.2009.03.014
URL: http://www.ncbi.nlm.nih.gov/pubmed/19497285

Induced pluripotent stem cells as a source for multipotent ISL1+cardiovascular progenitors

Journal: HUMAN GENE THERAPY

Published: 30/11/2008
URL:

Klf4 reverts developmentally programmed restriction of ground state pluripotency.

Journal: Development

Published: 30/11/2008
DOI: 10.1242/dev.030957
URL: http://www.ncbi.nlm.nih.gov/pubmed/19224983

Naive and primed pluripotent states.

Journal: Cell Stem Cell

Published: 30/11/2008
DOI: 10.1016/j.stem.2009.05.015
URL: http://www.ncbi.nlm.nih.gov/pubmed/19497275

Nanog is the gateway to the pluripotent ground state.

Journal: Cell

Published: 30/11/2008
DOI: 10.1016/j.cell.2009.07.039
URL: http://www.ncbi.nlm.nih.gov/pubmed/19703398

Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.

Journal: Cell Stem Cell

Published: 30/11/2008
DOI: 10.1016/j.stem.2009.11.003
URL: http://www.ncbi.nlm.nih.gov/pubmed/19951688

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo.

Journal: Development

Published: 30/11/2008
DOI: 10.1242/dev.038893
URL: http://www.ncbi.nlm.nih.gov/pubmed/19710168

Validated germline-competent embryonic stem cell lines from nonobese diabetic mice.

Journal: Nat Med

Published: 30/11/2008
DOI: 10.1038/nm.1996
URL: http://www.ncbi.nlm.nih.gov/pubmed/19491843

2007

Capture of authentic embryonic stem cells from rat blastocysts.

Journal: Cell

Published: 30/11/2007
DOI: 10.1016/j.cell.2008.12.007
URL: http://www.ncbi.nlm.nih.gov/pubmed/19109897

Capturing pluripotency.

Journal: Cell

Published: 30/11/2007
DOI: 10.1016/j.cell.2008.02.006
URL: http://www.ncbi.nlm.nih.gov/pubmed/18295569

Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation.

Journal: Mol Cell Neurosci

Published: 30/11/2007
DOI: 10.1016/j.mcn.2008.03.012
URL: http://www.ncbi.nlm.nih.gov/pubmed/18504136

Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture.

Journal: Mol Cell Neurosci

Published: 30/11/2007
DOI: 10.1016/j.mcn.2008.02.014
URL: http://www.ncbi.nlm.nih.gov/pubmed/18450476

Parameters influencing derivation of embryonic stem cells from murine embryos.

Journal: Genesis

Published: 30/11/2007
DOI: 10.1002/dvg.20442
URL: http://www.ncbi.nlm.nih.gov/pubmed/18837461

Promotion of reprogramming to ground state pluripotency by signal inhibition.

Journal: PLoS biology

Published: 30/11/2007
URL:

The ground state of embryonic stem cell self-renewal

Journal: NATURE

Published: 30/11/2007
DOI: 10.1038/nature06968
URL:

2006

Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells

Journal: Stem Cells

Published: 30/11/2006
DOI: 10.1634/stemcells.2006-0445
URL:

FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment

Journal: DEVELOPMENT

Published: 30/11/2006
DOI: 10.1242/dev.02880
URL:

Nanog safeguards pluripotency and mediates germline development.

Journal: Nature

Published: 30/11/2006
DOI: 10.1038/nature06403
URL: http://www.ncbi.nlm.nih.gov/pubmed/18097409

Neuroepithelial cells supply an initial transient wave of MSC differentiation.

Journal: Cell

Published: 30/11/2006
DOI: 10.1016/j.cell.2007.04.028
URL: http://www.ncbi.nlm.nih.gov/pubmed/17604725

Tripotential Differentiation of Adherently Expandable Neural Stem (NS) Cells

Journal: PLOS ONE

Published: 30/11/2006
DOI: 10.1371/journal.pone.0000298
URL:

2005

A glossary for stem-cell biology

Journal: NATURE

Published: 30/11/2005
DOI: 10.1038/Nature04954
URL:

Adherent neural stem (NS) cells from fetal and adult forebrain

Journal: Cerebral Cortex

Published: 30/11/2005
DOI: 10.1093/cercor/bbhj167
URL:

Embryonic stem cells: potency and potential

Journal: EMBO Science & Society paper, Stem Cell Research - Status Prospectus Prerequisites

Published: 30/11/2005
URL:

Exploitation of adherent neural stem cells in basic and applied neurobiology

Journal: REGENERATIVE MEDICINE

Published: 30/11/2005
DOI: 10.2217/17460751.1.1.111
URL:

Nanog promotes transfer of pluripotency after cell fusion.

Journal: Nature

Published: 30/11/2005
DOI: 10.1038/nature04914
URL: http://www.ncbi.nlm.nih.gov/pubmed/16791199

Notch promotes neural lineage entry by pluripotent embryonic stem cells

Journal: PLOS BIOL

Published: 30/11/2005
DOI: 10.1371/journal.pbio.0040121
URL:

Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus

Journal: Stem Cells

Published: 30/11/2005
DOI: 10.1634/stemcells.2006-0050
URL:

2004

Characterization of the uterine phenotype during the peri-implantation period for LIF-null, MF1 strain mice

Journal: DEVELOPMENTAL BIOLOGY

Published: 30/11/2004
DOI: 10.1016/j.ydbio.2005.01.033
URL:

Human embryonic stem cells

Journal: SCIENCE

Published: 30/11/2004
URL:

Niche-independent symmetrical self-renewal of a mammalian tissue stem cell

Journal: Plos Biology

Published: 30/11/2004
DOI: 10.1371/journal.pbio.0030283
URL:

Osteogenic and chondrogenic differentiation of embryonic stem cells in response to specific growth factors

Journal: Bone

Published: 30/11/2004
DOI: 10.1016/j.bone.2004.07.019
URL:

The battlefield of pluripotency

Journal: CELL

Published: 30/11/2004
DOI: 10.1016/j.cell.2005.11.012
URL:

Understanding embryonic stem cells

Journal: Placenta

Published: 30/11/2004
URL:

Unequal segregation of parental chromosomes in embryonic stem cell hybrids

Journal: Molecular Reproduction and Development

Published: 30/11/2004
DOI: 10.1002/Mrd.20266
URL:

2003

Control of ES cell self renewal and lineage specification, and medium therefore including rat ES cells

Published: 30/11/2003
URL:

Control of ES cell self renewal and lineage specification, and medium therefor

Published: 30/11/2003
URL:

Converting ES cells into neurons

Journal: Stem Cells in the Nervous System: Functional and Clinical Implications

Published: 30/11/2003
DOI: 10.1007/978-3-642-18883-1
ISBN: 978-3-642-18883-1
URL:

ES cells: Research progress in UK

Journal: Cell Technology (Japan)

Published: 30/11/2003
URL:

Identification of genes regulated by leukemia-inhibitory factor in the mouse uterus at the time of implantation.

Journal: Mol Endocrinol

Published: 30/11/2003
DOI: 10.1210/me.2004-0110
URL: http://www.ncbi.nlm.nih.gov/pubmed/15178747

Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar

Journal: Developmental Dynamics

Published: 30/11/2003
DOI: 10.1002/Dvdy.20003
URL:

Regulation of neural stem cells by beta amyloid in vitro

Journal: Neurobiology of Aging

Published: 30/11/2003
URL:

Regulation of uterine gene expression by leukaemia inhibitory factor

Journal: Biology of Reproduction

Published: 30/11/2003
URL:

Self-renewal of teratocarcinoma and embryonic stem cells

Journal: Oncogene

Published: 30/11/2003
DOI: 10.1038/sj.onc.1207930
URL:

SoxB transcription factors specify neuroectodermal lineage choice in ES cells

Journal: MOLECULAR AND CELLULAR NEUROSCIENCE

Published: 30/11/2003
DOI: 10.1016/j.mcn.2004.08.002
URL:

The differentiation of ES cells into neuroectodermal precursors is associated with an increase in the levels and sulfation of heparan sulfate proteoglycans

Journal: INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Published: 30/11/2003
URL:

2002

An unpaired mouse centromere passes consistently through male meiosis and does not significantly compromise spermatogenesis

Journal: Chromosoma

Published: 30/11/2002
DOI: 10.1007/s00412-003-0260-6
URL:

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

Journal: CELL

Published: 30/11/2002
URL:

Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

Journal: NATURE BIOTECHNOLOGY

Published: 30/11/2002
DOI: 10.1038/Nbt780
URL:

Defined conditions for neural commitment and differentiation

Journal: Methods in Enzymology

Published: 30/11/2002
URL:

Differentiation and gene regulation programming, reprogramming and regeneration – Editorial overview

Journal: CURRENT OPINION IN GENETICS & DEVELOPMENT

Published: 30/11/2002
DOI: 10.1016/j.gde.2003.08.013
URL:

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles

Journal: NATURE BIOTECHNOLOGY

Published: 30/11/2002
DOI: 10.1038/Nbt804
URL:

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

Journal: CELL

Published: 30/11/2002
URL:

Genesis of embryonic stem cells

Journal: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES

Published: 30/11/2002
DOI: 10.1098/rstb.2003.1327
URL:

Lineage allocation and asymmetries in the early mouse embryo – Discussion

Journal: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES

Published: 30/11/2002
URL:

Neural differentiation of mouse embryonic stem cells

Journal: BIOCHEMICAL SOCIETY TRANSACTIONS

Published: 30/11/2002
URL:

Rapid loss of Oct-4 and pluripotency in cultured rodent blastocysts and derivative cell lines

Journal: Biology of Reproduction

Published: 30/11/2002
DOI: 10.1095/biolreprod.102.006197
URL:

Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice

Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Published: 30/11/2002
DOI: 10.1073/pnas.1734197100
URL:

Specification of germ cell fate in mice.

Journal: Philos Trans R Soc Lond B Biol Sci

Published: 30/11/2002
DOI: 10.1098/rstb.2003.1324
URL: https://www.ncbi.nlm.nih.gov/pubmed/14511483

Stem cells – Fusion brings down barriers

Journal: NATURE

Published: 30/11/2002
DOI: 10.1038/422823a
URL:

The role of Oct-4 in early post-implantation development

Journal: Genetical Research

Published: 30/11/2002
URL:

2001

Changing potency by spontaneous fusion

Journal: NATURE

Published: 30/11/2001
URL:

Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation

Journal: NATURE BIOTECHNOLOGY

Published: 30/11/2001
DOI: 10.1038/Nbt763
URL:

Human embryonic stem cells: prospects for human health – a 1-day international symposium held at the University of Sheffield

Journal: Journal of Anatomy

Published: 30/11/2001
URL:

Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells

Journal: Journal of Cell Science

Published: 30/11/2001
DOI: 10.1242/Jcs.00049
URL:

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells

Journal: MOLECULAR AND CELLULAR BIOLOGY

Published: 30/11/2001
URL:

Signalling, cell cycle and pluripotency in embryonic stem cells

Journal: Trends in Cell Biology

Published: 30/11/2001
URL:

Targeted inactivation of the mouse locus encoding coagulation factor XIII-A: Hemostatic abnormalities in mutant mice and characterization of the coagulation deficit

Journal: THROMBOSIS AND HAEMOSTASIS

Published: 30/11/2001
URL:

2000

Embryo-derived stem cells: Of mice and men

Journal: Annual Review of Cell and Developmental Biology

Published: 30/11/2000
URL:

Embryonic Stem Cells

Journal: Stem cell biology

Published: 30/11/2000
ISBN: 978-0879695750
URL:

Lineage selection and isolation of neural precursor from embryonic stem cells

Journal: Brain Stem Cells

Published: 30/11/2000
URL:

Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines

Journal: DEVELOPMENT

Published: 30/11/2000
URL:

Self-renewal and differentiation of pluripotent embryonic stem cells.

Journal: DEVELOPMENTAL BIOLOGY

Published: 30/11/2000
URL:

1999

A structurally defined mini-chromosome vector for the mouse germ line

Journal: Current Biology

Published: 30/11/1999
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10660300

Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice

Journal: Neuron

Published: 30/11/1999
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10839370

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Journal: Nature Genetics

Published: 30/11/1999
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10742100

1998

Adaptive responses to environmental chemicals.

Journal: Biochem Soc Symp

Published: 30/11/1998
URL: https://www.ncbi.nlm.nih.gov/pubmed/10207626

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

Journal: Science

Published: 30/11/1998
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10558995

Leukemia inhibitory factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade

Journal: Journal of Biological Chemistry

Published: 30/11/1998
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10455174

New prospects for human stem-cell therapy in the nervous system.

Journal: Trends Neurosci

Published: 30/11/1998
URL: http://www.ncbi.nlm.nih.gov/pubmed/10407421

Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells

Journal: Cells, Tissues, Organs

Published: 30/11/1998
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10592385

Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses

Journal: European Journal of Immunology

Published: 30/11/1998
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10229092

Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells

Journal: Developmental Biology

Published: 30/11/1998
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10364425

1997

Cell Therapy: In search of pluripotency

Journal: Current Biology

Published: 30/11/1997
URL:

Differential stability of a human mini-chromosome in mouse cell lines

Journal: Chromosoma

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9745051

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

Journal: Cell

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9814708

Generation of purified neural precursors from embryonic stem cells by lineage selection

Journal: Current Biology

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9742400

Histochemical and ultrastructural modification of mucosal mast cell granules in parasitized mice lacking the beta-chymase, mouse mast cell protease-1

Journal: The American Journal of Pathology

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9708809

Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases

Journal: Proceedings of the National Academy of Sciences of USA

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9560266

Maintenance of pluripotential embryonic stem cells by stem cell selection

Journal: Reproduction Fertility and Development

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10612458

Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway

Journal: Developmental Biology

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9806780

Rat and mouse epiblasts differ in their capacity to generate extraembryonic endoderm

Journal: Reproduction Fertility and Development

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10612457

Rat and mouse epiblasts differ in their capacity to generate extraembryonic endoderm.

Journal: Reprod Fertil Dev

Published: 30/11/1997
URL: https://www.ncbi.nlm.nih.gov/pubmed/10612457

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Journal: Genes and Development

Published: 30/11/1997
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9649508

The use of transgenic animals to assess the role of metabolism in target organ toxicity

Journal: Archives of toxicology. Supplement.

Published: 30/11/1997
URL:

1996

A Schwann cell mitogen accompanying regeneration of motor neurons.

Journal: Nature

Published: 30/11/1996
DOI: 10.1038/37615
URL: http://www.ncbi.nlm.nih.gov/pubmed/9403691

Differentiation of embryonic stem cells into adipocytes in vitro

Journal: Cell Science

Published: 30/11/1996
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9202388

HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice

Journal: Journal of Experimental Medicine

Published: 30/11/1996
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9182675

Human mini-chromosomes in mouse embryonal stem cells

Journal: Human Molecular Genetics

Published: 30/11/1996
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9259287

Improved EBV-based shuttle vector system: dicistronic mRNA couples the synthesis of the Epstein-Barr nuclear antigen-1 protein to neomycin resistance

Journal: Genes and Development

Published: 30/11/1996
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9332352

Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos

Journal: Proceedings of the National Academy of Sciences of USA

Published: 30/11/1996
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9275227

Muller-cell-derived leukaemia inhibitory factor arrests rod photoreceptor differentiation at a postmitotic pre-rod stage of development

Journal: Development

Published: 30/11/1996
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9199361

Structure of the mouse leukaemia inhibitory factor receptor gene: regulated expression of mRNA encoding a soluble receptor isoform from an alternative 5′ untranslated region

Journal: Biochemical Journal

Published: 30/11/1996
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9396734

1995

Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis

Journal: Mechanisms of Development

Published: 30/11/1995
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8843390

Identification of a developmentally regulated protein tyrosine phosphatase in embryonic stem cells that is a marker of pluripotential epiblast and early mesoderm

Journal: Mechanisms of Development

Published: 30/11/1995
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8951793

1994

Altered immune responses in mice lacking inducible nitric oxide synthase

Journal: Nature

Published: 30/11/1994
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7539113

Essential function of LIF receptor in motor neurons

Journal: Nature

Published: 30/11/1994
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7501019

Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis

Journal: Trends in Genetics

Published: 30/11/1994
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7540337

1993

Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor

Journal: Experimental Cell Research

Published: 30/11/1993
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7957676

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression

Journal: Proceedings of the National Academy of Sciences

Published: 30/11/1993
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8183905

Embryonic Stem Cells and Haematopoiesis

Journal: Culture of hematopoietic cells

Published: 30/11/1993
ISBN: 9780471588306
URL:

Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways

Journal: Mechanisms of Development

Published: 30/11/1993
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8199053

1992

Expression of alternative forms of differentiation inhibiting activity (DIA/LIF) during murine embryogenesis and in neonatal and adult tissues

Journal: Developmental Genetics

Published: 30/11/1992
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7689430

Telomere directed fragmentation of mammalian chromosomes

Journal: Nuclei Acids Research

Published: 30/11/1992
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8441617

The responsiveness of embryonic stem cells to alpha and beta interferons provides the basis of an inducible expression system for analysis of developmental control genes

Journal: Molecular and Cellular Biology

Published: 30/11/1992
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8247011

1991

A rapid and efficient method for freezing and recovering clones of embryonic stem cells

Journal: Trends in Genetics

Published: 30/11/1991
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1369735

Differentiation inhibiting activity (DIA/LIF) and mouse development

Journal: Developmental Biology

Published: 30/11/1991
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1601171

Introduction: Mammalian Stem Cell Systems

Journal: Seminars in Cell Biology

Published: 30/11/1991
DOI: 10.1016/1043-4682(92)90009-K
URL:

Mouse embryo stem cells: their identification, propagation and manipulation

Journal: Seminars in Cell Biology

Published: 30/11/1991
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1489971

1990

Culture and Differentiation of Embryonic Stem Cells

Journal: Methods in Cell Science

Published: 30/11/1990
URL:

Embryonic stem cells, differentiation inhibiting activity, and the mouse embryo.

Journal: Seminars in Cell Biology

Published: 30/11/1990
URL:

1989

Developmentally programmed induction of differentiation inhibiting activity and the control of stem cell populations

Journal: Genes and Development

Published: 30/11/1989
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1703981

Differentiation inhibiting activity is produced in matrix-associated and diffusible forms that are generated by alternate promoter usage

Journal: Cell

Published: 30/11/1989
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2119255

Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity

Journal: Development (Cambridge)

Published: 30/11/1989
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2129226

Growth and Differentiation factors in embryonic stem cell function

Journal: Journal of Cell Science Suplement

Published: 30/11/1989
URL:

Leukemia inhibitory factor LIF/Differentiation-Inhibiting activity (DIA)/human interleukin for DA cells (HILDA) augments proliferation of human hematopoietic cells.

Journal: Blood

Published: 30/11/1989
URL:

1988

Growth and differentiation factors of embryonic stem cells

Journal: Cell to cell signalling in mammalian Development

Published: 30/11/1988
URL:

Growth factors in embryogenesis

Journal: British Medical Bulletin

Published: 30/11/1988
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2688809

1987

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

Journal: Nature

Published: 30/11/1987
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3143917

Regulatory factors of embryonic stem cells

Journal: J Cell Sci Suppl

Published: 30/11/1987
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3077939

1986

Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells

Journal: Developmental Biology

Published: 30/11/1986
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3569655

1985

Selection of a mouse embryonal carcinoma clone resistant to the inhibition of metabolic cooperation by retinoic acid

Journal: Experimental Cell Research

Published: 30/11/1985
URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3720856