Living Systems Institute

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Small but mighty: the power of microcrystals in structural biology

Journal: IUCrJ
Published:
URL: https://doi.org/10.1107/S2052252525001484
LSI Authors:
William Stuart
Prof Nicholas Harmer
Courtney Tremlett

Neural mass modeling reveals that hyperexcitability underpins slow‐wave sleep changes in children with epilepsy

Journal: Epilepsia
Published:
URL: https://doi.org/10.1111/epi.18293
LSI Authors:
Dr Marc Goodfellow
Prof Nicholas Harmer

Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes

Journal: Diabetologia
Published:
URL: https://doi.org/10.1007/s00125-025-06376-9
LSI Authors:
Dr Nicolas Verschueren Van Rees
Dr Kyle Wedgwood

Competition with Pseudomonas aeruginosa induces Staphylococcus aureus in an antibiotic-tolerant viable but non culturable state

Published:
URL: https://doi.org/10.1101/2025.04.30.651255
LSI Authors:
Dr Thomas Tunstall
Dr Sophia Zborowsky
Dr Urszula Lapinska

Competition withPseudomonas aeruginosainducesStaphylococcus aureusin an antibiotic-tolerant viable but non culturable state

Published:
URL: https://doi.org/10.1101/2025.04.30.651255
LSI Authors:
Dr Sophia Zborowsky
Dr Urszula Lapinska
Dr Thomas Tunstall

A near-term quantum simulation of the transverse field Ising model hints at glassy dynamics

Journal: The European Physical Journal Special Topics
Published:
URL: https://doi.org/10.1140/epjs/s11734-025-01630-y
LSI Authors:
Farhan Chowdhury

Optimised genome editing for precise DNA insertion and substitution using Prime Editors in zebrafish

Published:
URL: https://doi.org/10.1101/2025.04.23.650248
LSI Authors:
Dr Yosuke Ono
Prof Steffen Scholpp
Laraib Zaidi

Insulated Outlier Chromosomes Drive Metabolic and Evolutionary Innovation in Minimal Eukaryotic Algae

Published:
URL: https://doi.org/10.1101/2025.04.21.649811
LSI Authors:
Keith Harrison
Dr Adam Monier

Fully personalized modelling of Duchenne Muscular Dystrophy ambulation

Journal: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Published:
URL: https://doi.org/10.1098/rsta.2024.0218
LSI Authors:
Victor Applebaum
Dr Kyle Wedgwood
Prof Krasimira Tsaneva-Atanasova

A systematic review of the role of quantitative CT in the prognostication and disease monitoring of interstitial lung disease

Journal: European Respiratory Review
Published:
URL: https://doi.org/10.1183/16000617.0194-2024
LSI Authors:
Prof Krasimira Tsaneva-Atanasova