Living Systems Institute

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Single-cell microfluidics facilitates the rapid quantification of antibiotic accumulation in Gram-negative bacteria.

Journal: Lab on a chip
Published:
URL: http://europepmc.org/abstract/med/32613221

scReQTL: an approach to correlate SNVs to gene expression from individual scRNA-seq datasets

Published:
URL: http://europepmc.org/abstract/PPR/PPR186916

Structural effects of the highly protective V127 polymorphism on human prion protein

Journal: Communications Biology
Published:
LSI Authors:
Dr Becky Conners

Modeling of Wnt-mediated tissue patterning in vertebrate embryogenesis

Journal: PLOS Computational Biology
Published:
URL: http://dx.doi.org/10.1371/journal.pcbi.1007417

Embryonic stem cells commit to differentiation by symmetric divisions following a variable lag period

Published:
URL: https://doi.org/10.1101/2020.06.17.157578
LSI Authors:
Prof Austin Smith

Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by the nucleosome remodelling and deacetylation complex.

Journal: Elsevier BV
Published:

Termination of Transcription by RNA Polymerase II: BOOM!

Journal: Trends in genetics : TIG
Published:
URL: http://europepmc.org/abstract/med/32527618
LSI Authors:
Prof Steven West

Novel venom-based peptides (P13 and its derivative—M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways

Journal: Stem Cell Research & Therapy
Published:
URL: http://dx.doi.org/10.1186/s13287-020-01766-9
LSI Authors:
Dr Zhili Ren

Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity.

Journal: Nature communications
Published:
URL: http://europepmc.org/abstract/med/32499486

Cytoplasmic pool of spliceosome protein SNRNP70 regulates the axonal transcriptome and development of motor connectivity

Published:
URL: https://doi.org/10.1101/2020.05.25.097444