Living Systems Institute

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Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control.

Journal: Cell reports
Published:
URL: http://europepmc.org/abstract/med/30840897
LSI Authors:
Prof Steven West

Planarian flatworms as a new model system for understanding the epigenetic regulation of stem cell pluripotency and differentiation

Journal: Seminars in Cell & Developmental Biology
Published:
URL: http://dx.doi.org/10.1016/j.semcdb.2018.04.007
LSI Authors:
Dr Anish Dattani

A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity

Published:
URL: https://doi.org/10.1101/548628

Adeno-associated virus 2 bound to its cellular receptor AAVR

Journal: Nature Microbiology
Published:
URL: http://dx.doi.org/10.1038/s41564-018-0356-7
LSI Authors:
Dr William Stuart

Long‐Term Perfusion Culture of Monoclonal Embryonic Stem Cells in 3D Hydrogel Beads for Continuous Optical Analysis of Differentiation

Journal: Small
Published:
URL: http://dx.doi.org/10.1002/smll.201804576
LSI Authors:
Dr Fabrice Gielen

Carbohydrate Kinases: A Conserved Mechanism Across Differing Folds

Journal: Catalysts
Published:
URL: http://www.mdpi.com/2073-4344/9/1/29

A common molecular logic determines embryonic stem cell self‐renewal and reprogramming

Journal: The EMBO Journal
Published:
URL: https://doi.org/10.15252/embj.2018100003
LSI Authors:
Prof Austin Smith

The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling.

Journal: Cell reports
Published:
URL: http://europepmc.org/abstract/med/30650359

Zoonoses under our noses

Journal: Microbes and Infection
Published:
URL: http://dx.doi.org/10.1016/j.micinf.2018.06.001

The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea.

Journal: PLoS genetics
Published:
URL: http://europepmc.org/articles/PMC6312358
LSI Authors:
Dr Jordi Solana