Living Systems Institute

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Harnessing droplet microfluidics and morphology-based deep learning for the label-free study of polymicrobial-phage interactions

Published:
URL: https://doi.org/10.1101/2025.03.24.644924
LSI Authors:
Dr Fabrice Gielen
Prof Nicholas Harmer

The positionally conserved lncRNA DANCR is an essential regulator of zebrafish development and a human melanoma oncogene

Published:
URL: http://dx.doi.org/10.1101/2025.03.21.644561
LSI Authors:
Dr Stephanie Jones

How Does the Archaellum Work?

Journal: Biomolecules
Published:
URL: https://doi.org/10.3390/biom15040465
LSI Authors:
Dr Bertram Daum
Prof Nicholas Harmer

Structure and dynamics of macrophage infectivity potentiator proteins from pathogenic bacteria and protozoans bound to fluorinated pipecolic acid inhibitors

Journal: Journal of Medicinal Chemistry
Published:
URL: http://dx.doi.org/10.1021/acs.jmedchem.5c00134
LSI Authors:
Prof Nicholas Harmer

Decoding uncertainty for clinical decision-making

Journal: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Published:
URL: https://doi.org/10.1098/rsta.2024.0207
LSI Authors:
Prof Krasimira Tsaneva-Atanasova

The Hydractinia cell atlas reveals cellular and molecular principles of cnidarian coloniality.

Journal: Nature communications
Published:
URL: http://europepmc.org/abstract/med/40032860
LSI Authors:
Dr Jordi Solana
Prof Nicholas Harmer

Establishment of an efficient one-step enzymatic synthesis of cyclic-2,3-diphosphoglycerate

Published:
URL: https://doi.org/10.1101/2025.02.21.639460
LSI Authors:
Prof Nicholas Harmer

Recalibrating Protection Factors Using Millisecond Hydrogen/Deuterium Exchange Mass Spectrometry

Journal: Analytical Chemistry
Published:
URL: https://doi.org/10.1021/acs.analchem.4c03631
LSI Authors:
Dr Jonathan Phillips
Prof Nicholas Harmer

Mutations in the riboflavin biosynthesis pathway confer resistance to furazolidone and abolish the synergistic interaction between furazolidone and vancomycin in Escherichia coli

Journal: Microbial Genomics
Published:
URL: https://doi.org/10.1099/mgen.0.001356
LSI Authors:
Dr Van Hung Vuong Le
Prof Nicholas Harmer

A scotophobic response characterised by body contraction and ciliary arrest inAcroporacoral larvae

Published:
URL: https://doi.org/10.1101/2025.02.06.636794
LSI Authors:
Dr Hannah Laeverenz-Schlogelhofer
Prof Nicholas Harmer
Professor Kirsty Wan