Living Systems Institute

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Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes.

Published:
URL: http://europepmc.org/abstract/med/23300480

A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1

Journal: PLoS ONE
Published:
LSI Authors:
Prof Austin Smith

Automated large-scale culture and medium-throughput chemical screen for modulators of proliferation and viability of human induced pluripotent stem cell-derived neuroepithelial-like stem cells.

Journal: J Biomol Screen
Published:
URL: https://www.ncbi.nlm.nih.gov/pubmed/23042076
LSI Authors:
Prof Austin Smith

Differentiation of human induced pluripotent stem cells into brown and white adipocytes: Role of Pax3

Journal: STEM CELLS
Published:
LSI Authors:
Prof Austin Smith

Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.

Journal: Cell
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/23582324
LSI Authors:
Prof Austin Smith

Identification of the Missing Pluripotency Mediator Downstream of Leukaemia Inhibitory Factor

Journal: The EMBO Journal
Published:
LSI Authors:
Prof Austin Smith

Naive pluripotency is associated with global DNA hypomethylation.

Journal: Nat Struct Mol Biol
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/23416945
LSI Authors:
Prof Austin Smith

Nanog heterogeneity: tilting at windmills?

Journal: Cell Stem Cell
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/23827703
LSI Authors:
Prof Austin Smith

Neural stem cells engrafted in the adult brain fuse with endogenous neurons.

Journal: Stem Cells Dev
Published:
URL: https://www.ncbi.nlm.nih.gov/pubmed/23009360
LSI Authors:
Prof Austin Smith

Rebuilding pluripotency from primordial germ cells

Journal: Stem Cell Reports
Published:
LSI Authors:
Prof Austin Smith