Living Systems Institute

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Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid

Journal: Neuroscience Research
Published:
LSI Authors:
Prof Austin Smith

JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency.

Journal: Nat Commun
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/22569365
LSI Authors:
Prof Austin Smith

Pluripotency in the embryo and in culture.

Journal: Cold Spring Harb Perspect Biol
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/22855723
LSI Authors:
Prof Austin Smith

Self-organizing circuitry and emergent computation in mouse embryonic stem cells.

Journal: Stem Cell Res
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/22169460
LSI Authors:
Prof Austin Smith

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington’s disease patients demonstrates mutation related enhanced lysosomal activity

Journal: NEUROBIOL DIS
Published:
LSI Authors:
Prof Austin Smith

The transcriptional and epigenomic foundations of ground state pluripotency.

Journal: Cell
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/22541430
LSI Authors:
Prof Austin Smith

Treatment of a Mouse Model of Spinal Cord Injury by Transplantation of Human iPS Cell-derived Long-term Self-renewing Neuroepithelial-like Stem Cells

Journal: STEM CELLS
Published:
URL: http://dx.doi.org/10.1002/stem.1083
LSI Authors:
Prof Austin Smith

A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes

Journal: PLoS genetics
Published:
URL: http://europepmc.org/articles/PMC3320604
LSI Authors:
Dr Akshay Bhinge

An integrated encyclopedia of DNA elements in the human genome

Journal: Nature
Published:
URL: http://europepmc.org/articles/PMC3439153
LSI Authors:
Dr Akshay Bhinge

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

Journal: Genome research
Published:
URL: http://europepmc.org/articles/PMC3246210
LSI Authors:
Dr Akshay Bhinge