Living Systems Institute

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Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells.

Journal: Biol Open
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/23213369
LSI Authors:
Prof Austin Smith

Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal.

Journal: Cell Stem Cell
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/23040478
LSI Authors:
Prof Austin Smith

Germline potential of parthenogenetic haploid mouse embryonic stem cells.

Journal: Development
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/22912412
LSI Authors:
Prof Austin Smith

Human hypoblast formation is not dependent on FGF signalling

Journal: DEV BIOL
Published:
LSI Authors:
Prof Austin Smith

Imaging, quantification and visualization of spatio-temporal patterning in mESC colonies under different culture conditions

Journal: BIOINFORMATICS
Published:
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000308532300037&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=940c5db9f6a527ba8e12659dac275555
LSI Authors:
Prof Austin Smith

Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid

Journal: Neuroscience Research
Published:
LSI Authors:
Prof Austin Smith

JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency.

Journal: Nat Commun
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/22569365
LSI Authors:
Prof Austin Smith

Pluripotency in the embryo and in culture.

Journal: Cold Spring Harb Perspect Biol
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/22855723
LSI Authors:
Prof Austin Smith

Self-organizing circuitry and emergent computation in mouse embryonic stem cells.

Journal: Stem Cell Res
Published:
URL: http://www.ncbi.nlm.nih.gov/pubmed/22169460
LSI Authors:
Prof Austin Smith

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington’s disease patients demonstrates mutation related enhanced lysosomal activity

Journal: NEUROBIOL DIS
Published:
LSI Authors:
Prof Austin Smith